Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver.
Ablation of glycosylated lysosomal membrane protein (GLMP, formerly known as NCU-G1) has been shown to cause chronic liver injury which progresses into liver fibrosis in mice. Both lysosomal dysfunction and chronic liver injury can cause metabolic dysregulation. Glmp gt/gt mice (formerly known as Nc...
Main Authors: | Xiang Yi Kong, Eili Tranheim Kase, Anette Herskedal, Camilla Schjalm, Markus Damme, Cecilie Kasi Nesset, G Hege Thoresen, Arild C Rustan, Winnie Eskild |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4457871?pdf=render |
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