Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver.

Ablation of glycosylated lysosomal membrane protein (GLMP, formerly known as NCU-G1) has been shown to cause chronic liver injury which progresses into liver fibrosis in mice. Both lysosomal dysfunction and chronic liver injury can cause metabolic dysregulation. Glmp gt/gt mice (formerly known as Nc...

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Bibliographic Details
Main Authors: Xiang Yi Kong, Eili Tranheim Kase, Anette Herskedal, Camilla Schjalm, Markus Damme, Cecilie Kasi Nesset, G Hege Thoresen, Arild C Rustan, Winnie Eskild
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4457871?pdf=render

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