Changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgery
BackgroundLaparoscopic gastrectomy requires a reverse-Trendelenburg position and prolonged pneumoperitoneum and it could cause significant changes in cerebral homeostasis and lead to cognitive dysfunction. We compared changes in regional cerebral oxygen saturation (rSO2), early postoperative cogniti...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Korean Society of Anesthesiologists
2016-02-01
|
Series: | Korean Journal of Anesthesiology |
Subjects: | |
Online Access: | http://ekja.org/upload/pdf/kjae-69-44.pdf |
id |
doaj-0b40d5da991c4b668339026d59a57dc8 |
---|---|
record_format |
Article |
spelling |
doaj-0b40d5da991c4b668339026d59a57dc82020-11-25T03:57:09ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632016-02-01691445010.4097/kjae.2016.69.1.448216Changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgeryYoun Yi Jo0Jong Yeop Kim1Mi Geum Lee2Seul Gi Lee3Hyun Jeong Kwak4Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Incheon, Korea.Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Korea.Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Incheon, Korea.Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Korea.Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Incheon, Korea.BackgroundLaparoscopic gastrectomy requires a reverse-Trendelenburg position and prolonged pneumoperitoneum and it could cause significant changes in cerebral homeostasis and lead to cognitive dysfunction. We compared changes in regional cerebral oxygen saturation (rSO2), early postoperative cognitive function and hemodynamic variables in patients undergoing laparoscopic gastrectomy with those patients that underwent conventional open gastrectomy.MethodsSixty patients were enrolled in this study and the patients were distributed to receive either laparoscopic gastrectomy (laparoscopy group, n = 30) or open conventional gastrectomy (open group, n = 30). rSO2, end-tidal carbon dioxide tension, hemodynamic variables and arterial blood gas analysis were monitored during the operation. The enrolled patients underwent the mini-mental state examination 1 day before and 5 days after surgery for evaluation of early postoperative cognitive function.ResultsCompared to baseline value, rSO2 and end-tidal carbon dioxide tension increased significantly in the laparoscopy group after pneumoperitoneum, whereas no change was observed in the open group. No patient experienced cerebral oxygen desaturation or postoperative cognitive dysfunction. Changes in mean arterial pressure over time were significantly different between the groups (P < 0.001).ConclusionsBoth laparoscopic and open gastrectomy did not induce cerebral desaturation or early postoperative cognitive dysfunction in patients under desflurane anesthesia. However, rSO2 values during surgery favoured laparoscopic surgery, which was possibly related to increased cerebral blood flow due to increased carbon dioxide tension and the effect of a reverse Trendelenburg position.http://ekja.org/upload/pdf/kjae-69-44.pdfcerebral oxygen saturationlaparoscopic gastrectomypostoperative cognitive function |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Youn Yi Jo Jong Yeop Kim Mi Geum Lee Seul Gi Lee Hyun Jeong Kwak |
spellingShingle |
Youn Yi Jo Jong Yeop Kim Mi Geum Lee Seul Gi Lee Hyun Jeong Kwak Changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgery Korean Journal of Anesthesiology cerebral oxygen saturation laparoscopic gastrectomy postoperative cognitive function |
author_facet |
Youn Yi Jo Jong Yeop Kim Mi Geum Lee Seul Gi Lee Hyun Jeong Kwak |
author_sort |
Youn Yi Jo |
title |
Changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgery |
title_short |
Changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgery |
title_full |
Changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgery |
title_fullStr |
Changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgery |
title_full_unstemmed |
Changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgery |
title_sort |
changes in cerebral oxygen saturation and early postoperative cognitive function after laparoscopic gastrectomy: a comparison with conventional open surgery |
publisher |
Korean Society of Anesthesiologists |
series |
Korean Journal of Anesthesiology |
issn |
2005-6419 2005-7563 |
publishDate |
2016-02-01 |
description |
BackgroundLaparoscopic gastrectomy requires a reverse-Trendelenburg position and prolonged pneumoperitoneum and it could cause significant changes in cerebral homeostasis and lead to cognitive dysfunction. We compared changes in regional cerebral oxygen saturation (rSO2), early postoperative cognitive function and hemodynamic variables in patients undergoing laparoscopic gastrectomy with those patients that underwent conventional open gastrectomy.MethodsSixty patients were enrolled in this study and the patients were distributed to receive either laparoscopic gastrectomy (laparoscopy group, n = 30) or open conventional gastrectomy (open group, n = 30). rSO2, end-tidal carbon dioxide tension, hemodynamic variables and arterial blood gas analysis were monitored during the operation. The enrolled patients underwent the mini-mental state examination 1 day before and 5 days after surgery for evaluation of early postoperative cognitive function.ResultsCompared to baseline value, rSO2 and end-tidal carbon dioxide tension increased significantly in the laparoscopy group after pneumoperitoneum, whereas no change was observed in the open group. No patient experienced cerebral oxygen desaturation or postoperative cognitive dysfunction. Changes in mean arterial pressure over time were significantly different between the groups (P < 0.001).ConclusionsBoth laparoscopic and open gastrectomy did not induce cerebral desaturation or early postoperative cognitive dysfunction in patients under desflurane anesthesia. However, rSO2 values during surgery favoured laparoscopic surgery, which was possibly related to increased cerebral blood flow due to increased carbon dioxide tension and the effect of a reverse Trendelenburg position. |
topic |
cerebral oxygen saturation laparoscopic gastrectomy postoperative cognitive function |
url |
http://ekja.org/upload/pdf/kjae-69-44.pdf |
work_keys_str_mv |
AT younyijo changesincerebraloxygensaturationandearlypostoperativecognitivefunctionafterlaparoscopicgastrectomyacomparisonwithconventionalopensurgery AT jongyeopkim changesincerebraloxygensaturationandearlypostoperativecognitivefunctionafterlaparoscopicgastrectomyacomparisonwithconventionalopensurgery AT migeumlee changesincerebraloxygensaturationandearlypostoperativecognitivefunctionafterlaparoscopicgastrectomyacomparisonwithconventionalopensurgery AT seulgilee changesincerebraloxygensaturationandearlypostoperativecognitivefunctionafterlaparoscopicgastrectomyacomparisonwithconventionalopensurgery AT hyunjeongkwak changesincerebraloxygensaturationandearlypostoperativecognitivefunctionafterlaparoscopicgastrectomyacomparisonwithconventionalopensurgery |
_version_ |
1724461665663057920 |