Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo.
A strict cell death control in the intestinal epithelium is indispensable to maintain barrier integrity and homeostasis. In order to achieve a balance between cell proliferation and cell death, a tight regulation of Caspase-8, which is a key player in controlling apoptosis, is required. Caspase-8 ac...
Main Authors: | Barbara Ruder, Claudia Günther, Michael Stürzl, Markus Friedrich Neurath, Ethel Cesarman, Gianna Ballon, Christoph Becker |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0228441 |
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