Development and validation of spectrophotometric method for phenylephrine hydrochloride estimation in nasal drops formulations

Development and validation of spectrophotometric method for phenylephrine hydrochloride estimation in nasal drops formulations

Simple, accurate and reproducible UV-spectrophotometric method was developed and validated for the estimation of phenylephrine hydrochloride in pharmaceutical nasal drops formulations. Phenylephrine hydrochloride was estimated at 291 nm in 1 mol⋅dm-3 sodium hydroxide (pH 13.5). Beer’s law was obeyed...

Full description

Bibliographic Details
Main Authors:	Ivana Savić, Goran Nikolić, Vladimir Banković
Format:	Article
Language:	English
Published:	Society of Chemists and Technologists of Macedonia 2008-12-01
Series:	Macedonian Journal of Chemistry and Chemical Engineering
Subjects:	phenylephrine hydrochloride spectrophotometry nasal drops
Online Access:	https://mjcce.org.mk/index.php/MJCCE/article/view/235

Similar Items

THE SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF TRIMAZOLIN AND PHENYLEPHRINE HYDROCHLORIDE IN NASAL PREPARATIONS
by: Ivana Savić, et al.
Published: (2008-11-01)

Spectrophotometric determination of Phenylephrine hydrochloride and Salbutamol sulphate drugs in pharmaceutical preparations using diazotized Metoclopramide hydrochloride
by: Baghdad Science Journal
Published: (2015-03-01)

Spectrophotometric Assay of Phenylephrine hydrochloride in Pharmaceutical Formulation with Alizarin Red sulphonate in Aqueous Solution
by: Thabit Al-Ghabsha, et al.
Published: (2013-12-01)

An alternative synthesis of (±)-phenylephrine hydrochloride
by: Aphiwat Teerawutgulrag, et al.
Published: (2014-03-01)

Spectrophotometric Assay of Phenylephrine Hydrochloride Using 4-Aminoantipyrine and Copper (II)
by: Theia'a N. Al-Sabha
Published: (2010-06-01)

Revisiting the impact of phenylephrine hydrochloride on static and dynamic accommodation
by: Samrat Sarkar, et al.
Published: (2012-01-01)

Simultaneous determination of chlorpheniramine maleate, phenylephrine hydrochloride, paracetamol and caffeine in pharmaceutical preparation by RP-HPLC
by: Redasani V.K., et al.
Published: (2013-01-01)

Compatibility study of paracetamol, chlorpheniramine maleate and phenylephrine hydrochloride in physical mixtures
by: G.G.G. de Oliveira, et al.
Published: (2017-01-01)

Separation and simultaneous determination of paracetamol, phenylephrine hydrochloride and chlorpheniramine maleate in a commercial tablet by a rapid isocratic HPLC method
by: Afsaneh Nabi, et al.
Published: (2020-11-01)

A spectrophotometric micro determination of pyridoxine hydrochloride by coupling diazometry
by: Mohammad Saleem Saleem, et al.
Published: (2013-12-01)

Phenylephrine as an alternative to cocaine for nasal vasoconstriction before nasal surgery: A randomised trial
by: Sawsan T AlHaddad, et al.
Published: (2013-01-01)

Spectrophotometric determination of procainamide hydrochloride using sodium periodate
by: S. Al-Tamrah, et al.
Published: (2015-09-01)

Voltammetric determination of phenylephrine hydrochloride using a multi-walled carbon nanotube-modified carbon paste electrode
by: Q. Zhou, et al.
Published: (2018-01-01)

Spectrophotometric investigation of the uranyl-phenylephrine system
by: Pavun Leposava, et al.
Published: (2007-01-01)

Spectrophotometric investigation of the uranyl–phenylephrine system
by: LEPOSAVA PAVUN, et al.
Published: (2007-08-01)

Spectrophotometric Determination of Thiamine hydrochloride Via Oxidative Coupling Reaction Using 4-Aminoantipyrine
by: Reem Al-Luhaiby, et al.
Published: (2020-12-01)

Validated green spectrophotometric kinetic method for determination of Clindamycin Hydrochloride in capsules
by: Shaza Affas, et al.
Published: (2021-04-01)

Quantitative estimation of trimazolin hydrochloride in pharmaceutical preparation by RP-HPLC method
by: Savić Ivana M., et al.
Published: (2009-01-01)

Development and Validation of an Assay Method for Ciprofloxacin Hydrochloride Determination in Combination Ear Drops
by: Livia Uncu, et al.
Published: (2019-12-01)

Development and validation of a novel RP-HPLC method for simultaneous determination of paracetamol, phenylephrine hydrochloride, caffeine, cetirizine and nimesulide in tablet formulation
by: A.P. Dewani, et al.
Published: (2015-07-01)

Spectrophotometric Assay of Bromhexine hydrochloride in Pure and in Pharmaceutical Dosage Forms by Diazometry Coupling Reaction
by: Salim Mohammed, et al.
Published: (2013-12-01)

Quality by design (QbD) approach to formulate in situ gelling system for nose to brain delivery of Fluoxetine hydrochloride: Ex-vivo and In-vivo study
by: Inayat Bashir Pathan, et al.

Effectiveness of Prophylactic Intranasal Phenylephrine in Prevention of Nasal Congestion and Hypotension after Spinal Anaesthesia in Obstetric Patients: A Randomised Double Blinded Study
by: Sankar Roy, et al.
Published: (2020-04-01)

Study of Acute Toxicity and Irritant Effect of Nasal Spray Naltrexone Hydrochloride
by: Yu. M. Domnina, et al.
Published: (2021-05-01)

RATIONALE FOR THE SELECTION OF AUXILIARY COMPONENTS FOR THE NALTREXONE HYDROCHLORIDE NASAL SPRAY
by: Y. M. Domnina, et al.
Published: (2019-01-01)

Selective Spectrophotometric Determination of Metformin Hydrochloride in Pharmaceuticals and Urine Using Two Nitrophenols as Chromogenic Agents
by: Kanakapura Basavaiah, et al.
Published: (2017-06-01)

Spectrophotometric determination of xylometazoline in nasal drops
by: А. О. Donchenko, et al.
Published: (2018-08-01)

The effect of phenylephrine on the onset time of rocuronium
by: Young Ju Won, et al.
Published: (2010-10-01)

Spectrophotometric estimation of betahistine hydrochloride in tablet formulations
by: Amit Kumar, et al.
Published: (2010-01-01)

Quantitative proton nuclear magnetic resonance method for simultaneous analysis of fluticasone propionate and azelastine hydrochloride in nasal spray formulation
by: Amal A. El-Masry, et al.
Published: (2021-07-01)

Sensitive extraction spectrophotometric methods for the determination of trazodone hydrochloride in pure and pharmaceutical formulations
by: Harikrishna K., et al.
Published: (2006-01-01)

Sensitive extraction spectrophotometric methods for the determination of trazodone hydrochloride in pure and pharmaceutical formulations
by: K. HARIKRISHNA, et al.
Published: (2006-07-01)

Quantification of naphazoline nitrate by UV-spectrophoto-metry
by: O. I. Panasenko, et al.
Published: (2013-12-01)

On the validity of using sympathomimetic drops in the treatment of habitually excessive tension of accommodation
by: T. N. Vorontsova, et al.
Published: (2018-10-01)

Bronchoconstriction following instillation of phenylephrine eye drops in premature infants with bronchopulmonary dysplasia: two cases report
by: Hyun Jee Kim, et al.
Published: (2015-12-01)

Adverse Cardiovascular Effects of Phenylephrine Eye Drops Combined With Intravenous Atropine
by: Qingyu Li, et al.
Published: (2021-01-01)

Fourth-order derivative spectrophotometric method for simultaneous determination of pseudoephedrine and naproxen in pharmaceutical dosage forms
by: Effat Souri, et al.
Published: (2016-01-01)

Use of alizarin red S as a chromogenic agent for the colorimetric determination of dothiepin hydrochloride in pharmaceutical formulations
by: Sameer A.M. Abdulrahman, et al.
Published: (2014-04-01)

Preparation, characterization, and in vivo pharmacokinetics of thermosensitive in situ nasal gel of donepezil hydrochloride
by: Gu Fugen, et al.
Published: (2020-09-01)

Quantitative determination of acetaminophen, phenylephrine and carbinoxamine in tablets by high-performance liquid chromatography
by: Carina de A. Bastos, et al.
Published: (2009-01-01)