Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry.
Recent genome-wide studies identified a risk locus for colorectal cancer at 18q21, which maps to the SMAD7 gene. Our objective was to confirm the association between SMAD7 SNPs and colorectal cancer risk in the multi-center Colon Cancer Family Registry.23 tagging SNPs in the SMAD7 gene were genotype...
Main Authors: | Xuejuan Jiang, J Esteban Castelao, David Vandenberg, Angel Carracedo, Carmen M Redondo, David V Conti, Jesus P Paredes Cotoré, John D Potter, Polly A Newcomb, Michael N Passarelli, Mark A Jenkins, John L Hopper, Steven Gallinger, Loic Le Marchand, María E Martínez, Dennis J Ahnen, John A Baron, Noralane M Lindor, Robert W Haile, Manuela Gago-Dominguez |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3616155?pdf=render |
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