Mutational analysis of epidermal and hyperproliferative type I keratins in mild and moderate psoriasis vulgaris patients: a possible role in the pathogenesis of psoriasis along with disease severity

Mutational analysis of epidermal and hyperproliferative type I keratins in mild and moderate psoriasis vulgaris patients: a possible role in the pathogenesis of psoriasis along with disease severity

Abstract Background Mutations in keratin proteins have been vastly associated with a wide array of genodermatoses; however, mutations of keratins in psoriasis have not been fully investigated. The main aim of the current research was to identify the mutation in K14, K10, K16, and K17 genes in two st...

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Bibliographic Details
Main Authors: Tamilselvi Elango, Jingying Sun, Caihong Zhu, Fusheng Zhou, Yaohua Zhang, Liangdan Sun, Sen Yang, Xuejun Zhang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Human Genomics
Subjects:
Epidermal keratins
Hyperproliferative keratins
Psoriasis
Mutation
Sanger sequence
Immunofluorescence
Online Access:http://link.springer.com/article/10.1186/s40246-018-0158-2

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http://link.springer.com/article/10.1186/s40246-018-0158-2

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