In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors

In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors

Accumulated evidence suggests that enhancing the endocannabinoid (eCB) tone, in particular of anandamide (<i>N</i>-arachidonoylethanolamine, AEA), has therapeutic potential in many human diseases. Fatty acid amide hydrolase (FAAH) is a membrane-bound enzyme principally responsible for th...

Full description

Bibliographic Details
Main Authors: Emanuele Criscuolo, Maria Laura De Sciscio, Filomena Fezza, Mauro Maccarrone
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
cannabinoids
docking
endocannabinoids
FAAH
inhibition
modeling
Online Access:https://www.mdpi.com/1420-3049/26/1/48

Similar Items

Similar Items