A method for functional trans-complementation of intracellular Francisella tularensis.

Francisella tularensis is a highly infectious bacterial pathogen that invades and replicates within numerous host cell types. After uptake, F. tularensis bacteria escape the phagosome, replicate within the cytosol, and suppress cytokine responses. However, the mechanisms employed by F. tularensis to...

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Bibliographic Details
Main Authors: Shaun Steele, Sharon Taft-Benz, Thomas Kawula
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913766?pdf=render