Organ-Specific Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitor Monotherapy Versus Combination Therapy in Cancer: A Meta-Analysis of Randomized Controlled Trials

Organ-Specific Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitor Monotherapy Versus Combination Therapy in Cancer: A Meta-Analysis of Randomized Controlled Trials

BackgroundAlthough combination therapy with immune checkpoint inhibitors (ICIs) provides a promising efficacy in multiple cancers, their use is facing challenges for a high incidence of adverse effects. This meta-analysis was conducted to compare the risks of organ-specific immune-related adverse ev...

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Bibliographic Details
Main Authors: Lijun Da, Yuanjun Teng, Na Wang, Karen Zaguirre, Yating Liu, Yali Qi, Feixue Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
immune checkpoint inhibitor
combination immunotherapy
organ specific
adverse events
meta-analysis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01671/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01671/full

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