Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function.

Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function.

In protein folding and secretion disorders, activation of endoplasmic reticulum (ER) stress signaling (ERSS) protects cells, alleviating stress that would otherwise trigger apoptosis. Whether the stress-surviving cells resume normal function is not known. We studied the in vivo impact of ER stress i...

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Bibliographic Details
Main Authors: Kwok Yeung Tsang, Danny Chan, Deborah Cheslett, Wilson C W Chan, Chi Leong So, Ian G Melhado, Tori W Y Chan, Kin Ming Kwan, Ernst B Hunziker, Yoshihiko Yamada, John F Bateman, Kenneth M C Cheung, Kathryn S E Cheah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0050044

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