Improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillation
Abstract Background Catheter ablation (CA) for atrial fibrillation (AF) is widely performed. However, the indication for CA in patients with asymptomatic persistent AF is still controversial. Methods Among 259 consecutive patients who were hospitalized for initial CA of AF, a total of 45 patients wh...
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doaj-0c075d27b7a2436d928d3d53cef2689b2021-03-06T06:11:15ZengWileyJournal of Arrhythmia1880-42761883-21482021-02-01371111910.1002/joa3.12457Improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillationNaoaki Onishi0Shokan Kyo1Maki Oi2Toshikazu Jinnai3Maiko Kuroda4Yukiko Shimizu5Sari Imamura6Takeshi Harita7Suguru Nishiuchi8Koji Hanazawa9Toshihiro Tamura10Chisato Izumi11Yoshihisa Nakagawa12Kazuaki Kaitani13Division of Cardiology Tenri Hospital Tenri JapanJapanese Red Cross Otsu Hospital Otsu JapanJapanese Red Cross Otsu Hospital Otsu JapanJapanese Red Cross Otsu Hospital Otsu JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanDivision of Cardiology Tenri Hospital Tenri JapanAbstract Background Catheter ablation (CA) for atrial fibrillation (AF) is widely performed. However, the indication for CA in patients with asymptomatic persistent AF is still controversial. Methods Among 259 consecutive patients who were hospitalized for initial CA of AF, a total of 45 patients who had asymptomatic persistent AF were retrospectively analyzed. Quality of life (QOL) before and 1 year after CA was evaluated, and changes in the cardiac function over 5 years after CA were also examined. QOL was assessed using the AF QOL questionnaire (AFQLQ) developed by the Japanese Heart Rhythm Society. In addition, cardiac function was assessed by measuring the plasma B‐type natriuretic peptide (BNP) level, left ventricular ejection fraction (LVEF), left atrial diameter (LAD) with transthoracic echocardiogram, and left atrial (LA) volume with computed tomography (CT). Results The AFQLQ significantly improved after CA in terms of “symptom frequency” and “activity limits and mental anxiety.” The plasma BNP level, LVEF, and LAD significantly improved in the first 3 months after the first CA, with no significant changes thereafter (from 149.0 pg/dL [95% confidence intervals {CI}, 114.5‐183.5 pg/dL] to 49.8 pg/dL [95% CI, 26.5‐70.1], P < .0001; from 60.8% [95% CI, 58.1%–63.6%] to 65.0% [95% CI, 62.6‐67.4], P = .001; and from 41.3 mm [95% CI, 39.7‐42.9] to 36.8 [95% CI, 34.5‐39.1 mm], P < .0001, respectively). LA volume revealed LA reverse remodeling after CA. Conclusion Improvement in the QOL and cardiac function after CA of asymptomatic persistent AF was revealed. Asymptomatic persistent AF should be appropriately treated by CA.https://doi.org/10.1002/joa3.12457atrial fibrillationB‐type natriuretic peptidecatheter ablationquality of lifereverse remodeling |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Naoaki Onishi Shokan Kyo Maki Oi Toshikazu Jinnai Maiko Kuroda Yukiko Shimizu Sari Imamura Takeshi Harita Suguru Nishiuchi Koji Hanazawa Toshihiro Tamura Chisato Izumi Yoshihisa Nakagawa Kazuaki Kaitani |
spellingShingle |
Naoaki Onishi Shokan Kyo Maki Oi Toshikazu Jinnai Maiko Kuroda Yukiko Shimizu Sari Imamura Takeshi Harita Suguru Nishiuchi Koji Hanazawa Toshihiro Tamura Chisato Izumi Yoshihisa Nakagawa Kazuaki Kaitani Improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillation Journal of Arrhythmia atrial fibrillation B‐type natriuretic peptide catheter ablation quality of life reverse remodeling |
author_facet |
Naoaki Onishi Shokan Kyo Maki Oi Toshikazu Jinnai Maiko Kuroda Yukiko Shimizu Sari Imamura Takeshi Harita Suguru Nishiuchi Koji Hanazawa Toshihiro Tamura Chisato Izumi Yoshihisa Nakagawa Kazuaki Kaitani |
author_sort |
Naoaki Onishi |
title |
Improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillation |
title_short |
Improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillation |
title_full |
Improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillation |
title_fullStr |
Improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillation |
title_full_unstemmed |
Improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillation |
title_sort |
improvement in quality of life and cardiac function after catheter ablation for asymptomatic persistent atrial fibrillation |
publisher |
Wiley |
series |
Journal of Arrhythmia |
issn |
1880-4276 1883-2148 |
publishDate |
2021-02-01 |
description |
Abstract Background Catheter ablation (CA) for atrial fibrillation (AF) is widely performed. However, the indication for CA in patients with asymptomatic persistent AF is still controversial. Methods Among 259 consecutive patients who were hospitalized for initial CA of AF, a total of 45 patients who had asymptomatic persistent AF were retrospectively analyzed. Quality of life (QOL) before and 1 year after CA was evaluated, and changes in the cardiac function over 5 years after CA were also examined. QOL was assessed using the AF QOL questionnaire (AFQLQ) developed by the Japanese Heart Rhythm Society. In addition, cardiac function was assessed by measuring the plasma B‐type natriuretic peptide (BNP) level, left ventricular ejection fraction (LVEF), left atrial diameter (LAD) with transthoracic echocardiogram, and left atrial (LA) volume with computed tomography (CT). Results The AFQLQ significantly improved after CA in terms of “symptom frequency” and “activity limits and mental anxiety.” The plasma BNP level, LVEF, and LAD significantly improved in the first 3 months after the first CA, with no significant changes thereafter (from 149.0 pg/dL [95% confidence intervals {CI}, 114.5‐183.5 pg/dL] to 49.8 pg/dL [95% CI, 26.5‐70.1], P < .0001; from 60.8% [95% CI, 58.1%–63.6%] to 65.0% [95% CI, 62.6‐67.4], P = .001; and from 41.3 mm [95% CI, 39.7‐42.9] to 36.8 [95% CI, 34.5‐39.1 mm], P < .0001, respectively). LA volume revealed LA reverse remodeling after CA. Conclusion Improvement in the QOL and cardiac function after CA of asymptomatic persistent AF was revealed. Asymptomatic persistent AF should be appropriately treated by CA. |
topic |
atrial fibrillation B‐type natriuretic peptide catheter ablation quality of life reverse remodeling |
url |
https://doi.org/10.1002/joa3.12457 |
work_keys_str_mv |
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