Metabolite profiling uncovers plasmid-induced cobalt limitation under methylotrophic growth conditions.
BACKGROUND:The introduction and maintenance of plasmids in cells is often associated with a reduction of growth rate. The reason for this growth reduction is unclear in many cases. METHODOLOGY/PRINCIPAL FINDINGS:We observed a surprisingly large reduction in growth rate of about 50% of Methylobacteri...
Main Authors: | Patrick Kiefer, Markus Buchhaupt, Philipp Christen, Björn Kaup, Jens Schrader, Julia A Vorholt |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-11-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2773004?pdf=render |
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