Metabolite profiling uncovers plasmid-induced cobalt limitation under methylotrophic growth conditions.

BACKGROUND:The introduction and maintenance of plasmids in cells is often associated with a reduction of growth rate. The reason for this growth reduction is unclear in many cases. METHODOLOGY/PRINCIPAL FINDINGS:We observed a surprisingly large reduction in growth rate of about 50% of Methylobacteri...

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Bibliographic Details
Main Authors: Patrick Kiefer, Markus Buchhaupt, Philipp Christen, Björn Kaup, Jens Schrader, Julia A Vorholt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2773004?pdf=render

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