Gas6 Prevents Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells via Production of PGE<sub>2</sub>, PGD<sub>2</sub> and Their Receptors

Gas6 Prevents Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells via Production of PGE<sub>2</sub>, PGD<sub>2</sub> and Their Receptors

The epithelial-mesenchymal transition (EMT) is important in organ fibrosis. We hypothesized that growth arrest-specific protein 6 (Gas6) and its underlying mechanisms play roles in the prevention of EMT in alveolar epithelial cells (ECs). In this study, to determine whether Gas6 prevents TGF-&#9...

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Bibliographic Details
Main Authors: Jihye Jung, Ye-Ji Lee, Youn-Hee Choi, Eun-Mi Park, Hee-Sun Kim, Jihee L. Kang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
Gas6
prostaglandins
epithelial-mesenchymal transition
alveolar epithelial cells
Online Access:https://www.mdpi.com/2073-4409/8/7/643

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