The Effect of Acupuncture on Visual Function in Patients with Congenital and Acquired Nystagmus
Background: The aim of this study is to examine the short-term effect of visual function following acupuncture treatment in patients with congenital idiopathic nystagmus and acquired nystagmus (CIN and AN). Methods: An observational pilot study on six patients with confirmed diagnosis of nystagmus (...
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doaj-0c40843d531c4e4983e891ce30af82e92020-11-25T00:59:01ZengMDPI AGMedicines2305-63202017-05-01423310.3390/medicines4020033medicines4020033The Effect of Acupuncture on Visual Function in Patients with Congenital and Acquired NystagmusTilo Blechschmidt0Maike Krumsiek1Margarita G. Todorova2Department of Ophthalmology, University of Basel, Mittlere Strasse 91, CH-4031 Basel, SwitzerlandDepartment of Ophthalmology, University of Basel, Mittlere Strasse 91, CH-4031 Basel, SwitzerlandDepartment of Ophthalmology, University of Basel, Mittlere Strasse 91, CH-4031 Basel, SwitzerlandBackground: The aim of this study is to examine the short-term effect of visual function following acupuncture treatment in patients with congenital idiopathic nystagmus and acquired nystagmus (CIN and AN). Methods: An observational pilot study on six patients with confirmed diagnosis of nystagmus (three CIN and three AN patients (2♀, 4♂; mean age 42.67; SD ± 20.57 y)), was performed. Acupuncture treatment was done following a standardized protocol applying needle-acupuncture on the body and the ears. The treatment was scheduled with 10 sessions of 30 min duration over five weeks. To assess the effect of the treatment, we performed before, between, and after acupuncture objective measurement of the BCVA (EDTRS charts), contrast vision (CSV-1000, Vector Vision), nystagmography (Compact Integrated Pupillograph), complemented by evaluation questionnaires. A placebo non-acupuncture control group (Nr: 11, 22 eyes; 8♀, 3♂; mean age: 33.34 y (SD ± 7.33 y)) was taken for comparison. Results: The results showed that, following acupuncture treatment, CIN and AN patients showed improvement (SD± mean) in their binocular BCVA (baseline: 0.45 ± 0.36; between: 0.53 ± 0.34 and post-treatment: 0.51 ± 0.28), and in their monocular contrast sensitivity (baseline: 11.29 ± 12.35; between: 11.43 ± 11.45 and post-treatment: 14.0 ± 12.22). The post-/baseline-difference showed a significant improvement in contrast vision and in BCVA for CIN and AN patients, but not for controls (p = 0.029 and p = 0.007, respectively). The effect of the eye showed also, within CIN and AN, significant values for the examined parameters in the post-/baseline difference (p = 0.004 and p ≤ 0.001). Evaluated only binocularly, the respective between-/baseline and post-/baseline difference in the CIN and AN group showed significant values (p < 0.045). Two AN patients reported reduction of oscillations. Among general subjective symptoms, our patients reported reduction of tiredness and headache attacks, improvement of vision, and shorter sleep onset time. Conclusion: The applied acupuncture protocol showed improvement in the visual function of nystagmus patients and thus, in their quality of life. Further studies are mandatory to differentiate which group of nystagmus patients would benefit more from acupuncture.http://www.mdpi.com/2305-6320/4/2/33acupuncturenystagmuscontrast visonvisual functionnystagmography |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tilo Blechschmidt Maike Krumsiek Margarita G. Todorova |
spellingShingle |
Tilo Blechschmidt Maike Krumsiek Margarita G. Todorova The Effect of Acupuncture on Visual Function in Patients with Congenital and Acquired Nystagmus Medicines acupuncture nystagmus contrast vison visual function nystagmography |
author_facet |
Tilo Blechschmidt Maike Krumsiek Margarita G. Todorova |
author_sort |
Tilo Blechschmidt |
title |
The Effect of Acupuncture on Visual Function in Patients with Congenital and Acquired Nystagmus |
title_short |
The Effect of Acupuncture on Visual Function in Patients with Congenital and Acquired Nystagmus |
title_full |
The Effect of Acupuncture on Visual Function in Patients with Congenital and Acquired Nystagmus |
title_fullStr |
The Effect of Acupuncture on Visual Function in Patients with Congenital and Acquired Nystagmus |
title_full_unstemmed |
The Effect of Acupuncture on Visual Function in Patients with Congenital and Acquired Nystagmus |
title_sort |
effect of acupuncture on visual function in patients with congenital and acquired nystagmus |
publisher |
MDPI AG |
series |
Medicines |
issn |
2305-6320 |
publishDate |
2017-05-01 |
description |
Background: The aim of this study is to examine the short-term effect of visual function following acupuncture treatment in patients with congenital idiopathic nystagmus and acquired nystagmus (CIN and AN). Methods: An observational pilot study on six patients with confirmed diagnosis of nystagmus (three CIN and three AN patients (2♀, 4♂; mean age 42.67; SD ± 20.57 y)), was performed. Acupuncture treatment was done following a standardized protocol applying needle-acupuncture on the body and the ears. The treatment was scheduled with 10 sessions of 30 min duration over five weeks. To assess the effect of the treatment, we performed before, between, and after acupuncture objective measurement of the BCVA (EDTRS charts), contrast vision (CSV-1000, Vector Vision), nystagmography (Compact Integrated Pupillograph), complemented by evaluation questionnaires. A placebo non-acupuncture control group (Nr: 11, 22 eyes; 8♀, 3♂; mean age: 33.34 y (SD ± 7.33 y)) was taken for comparison. Results: The results showed that, following acupuncture treatment, CIN and AN patients showed improvement (SD± mean) in their binocular BCVA (baseline: 0.45 ± 0.36; between: 0.53 ± 0.34 and post-treatment: 0.51 ± 0.28), and in their monocular contrast sensitivity (baseline: 11.29 ± 12.35; between: 11.43 ± 11.45 and post-treatment: 14.0 ± 12.22). The post-/baseline-difference showed a significant improvement in contrast vision and in BCVA for CIN and AN patients, but not for controls (p = 0.029 and p = 0.007, respectively). The effect of the eye showed also, within CIN and AN, significant values for the examined parameters in the post-/baseline difference (p = 0.004 and p ≤ 0.001). Evaluated only binocularly, the respective between-/baseline and post-/baseline difference in the CIN and AN group showed significant values (p < 0.045). Two AN patients reported reduction of oscillations. Among general subjective symptoms, our patients reported reduction of tiredness and headache attacks, improvement of vision, and shorter sleep onset time. Conclusion: The applied acupuncture protocol showed improvement in the visual function of nystagmus patients and thus, in their quality of life. Further studies are mandatory to differentiate which group of nystagmus patients would benefit more from acupuncture. |
topic |
acupuncture nystagmus contrast vison visual function nystagmography |
url |
http://www.mdpi.com/2305-6320/4/2/33 |
work_keys_str_mv |
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