Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient

A 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colono...

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Bibliographic Details
Main Authors: Jin Yu Chieng, Yasotha Sugumaran, Sellymiah Adzman, Pan Yan
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Gastroenterology Insights
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/gi/article/view/6886
Description
Summary:A 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colonoscopy showed moderate left sided colitis, with histopathology evidence of ulcerative colitis (UC) with cytomegalovirus (CMV) infection. Her serum anti-CMV IgM antibody was detected. She was treated with intravenous ganciclovir, together with 5-ASA and tapering dose of steroid. Anemia was corrected. Subsequent clinic reviews and follow up endoscopies showed dramatically improvement. CMV colitis should be considered for the patients presenting with moderate to severe UC. Early prescription of antiviral would be beneficial in the treatment of flare of UC.
ISSN:2036-7414
2036-7422