Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient
A 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colono...
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doaj-0c448d6790ce45539d92dfcc95148d972021-05-02T20:31:28ZengMDPI AGGastroenterology Insights2036-74142036-74222017-12-018110.4081/gi.2017.68863854Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patientJin Yu Chieng0Yasotha Sugumaran1Sellymiah Adzman2Pan Yan3Department of Medicine, Faculty of Medicine and Health Science, Universiti Putra Malaysia, SelangorDepartment of Medicine, Faculty of Medicine and Health Science, Universiti Putra Malaysia, SelangorDepartment of Pathology, Serdang Hospital, SelangorDepartment of Biomedical Science, The University of Nottingham, SemenyihA 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colonoscopy showed moderate left sided colitis, with histopathology evidence of ulcerative colitis (UC) with cytomegalovirus (CMV) infection. Her serum anti-CMV IgM antibody was detected. She was treated with intravenous ganciclovir, together with 5-ASA and tapering dose of steroid. Anemia was corrected. Subsequent clinic reviews and follow up endoscopies showed dramatically improvement. CMV colitis should be considered for the patients presenting with moderate to severe UC. Early prescription of antiviral would be beneficial in the treatment of flare of UC.http://www.pagepress.org/journals/index.php/gi/article/view/6886Cytomegalovirus, ulcerative colitis, antiviral |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jin Yu Chieng Yasotha Sugumaran Sellymiah Adzman Pan Yan |
spellingShingle |
Jin Yu Chieng Yasotha Sugumaran Sellymiah Adzman Pan Yan Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient Gastroenterology Insights Cytomegalovirus, ulcerative colitis, antiviral |
author_facet |
Jin Yu Chieng Yasotha Sugumaran Sellymiah Adzman Pan Yan |
author_sort |
Jin Yu Chieng |
title |
Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient |
title_short |
Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient |
title_full |
Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient |
title_fullStr |
Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient |
title_full_unstemmed |
Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient |
title_sort |
synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient |
publisher |
MDPI AG |
series |
Gastroenterology Insights |
issn |
2036-7414 2036-7422 |
publishDate |
2017-12-01 |
description |
A 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colonoscopy showed moderate left sided colitis, with histopathology evidence of ulcerative colitis (UC) with cytomegalovirus (CMV) infection. Her serum anti-CMV IgM antibody was detected. She was treated with intravenous ganciclovir, together with 5-ASA and tapering dose of steroid. Anemia was corrected. Subsequent clinic reviews and follow up endoscopies showed dramatically improvement. CMV colitis should be considered for the patients presenting with moderate to severe UC. Early prescription of antiviral would be beneficial in the treatment of flare of UC. |
topic |
Cytomegalovirus, ulcerative colitis, antiviral |
url |
http://www.pagepress.org/journals/index.php/gi/article/view/6886 |
work_keys_str_mv |
AT jinyuchieng synchronouscytomegalovirusinfectioninanewlydiagnosedulcerativecolitispatient AT yasothasugumaran synchronouscytomegalovirusinfectioninanewlydiagnosedulcerativecolitispatient AT sellymiahadzman synchronouscytomegalovirusinfectioninanewlydiagnosedulcerativecolitispatient AT panyan synchronouscytomegalovirusinfectioninanewlydiagnosedulcerativecolitispatient |
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1721487542784622592 |