Integrative genomics identifies new genes associated with severe COPD and emphysema

Integrative genomics identifies new genes associated with severe COPD and emphysema

Abstract Background Genome-wide association studies have identified several genetic risk loci for severe chronic obstructive pulmonary disease (COPD) and emphysema. However, these studies do not fully explain disease heritability and in most cases, fail to implicate specific genes. Integrative metho...

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Bibliographic Details
Main Authors: Phuwanat Sakornsakolpat, Jarrett D. Morrow, Peter J. Castaldi, Craig P. Hersh, Yohan Bossé, Edwin K. Silverman, Ani Manichaikul, Michael H. Cho
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Respiratory Research
Subjects:
Chronic obstructive pulmonary disease
Emphysema
Genome-wide association studies
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12931-018-0744-9

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