Analysis of the SNARE Stx8 recycling reveals that the retromer-sorting motif has undergone evolutionary divergence.
Fsv1/Stx8 is a Schizosaccharomyces pombe protein similar to mammalian syntaxin 8. stx8Δ cells are sensitive to salts, and the prevacuolar endosome (PVE) is altered in stx8Δ cells. These defects depend on the SNARE domain, data that confirm the conserved function of syntaxin8 and Stx8 in vesicle fusi...
Main Authors: | Francisco Yanguas, M-Henar Valdivieso |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-03-01
|
Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1009463 |
Similar Items
-
The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases
by: Hongfeng Zhang, et al.
Published: (2018-03-01) -
Navigating the Controversies of Retromer-Mediated Endosomal Protein Sorting
by: Yingfeng Tu, et al.
Published: (2021-06-01) -
Sorting Out the Role of α-Synuclein in Retromer-Mediated Endosomal Protein Sorting
by: Dhaval Patel, et al.
Published: (2018-08-01) -
Regulation of transmembrane protein recycling by the retromer complex
by: Tilley, Frances Catherine
Published: (2016) -
COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal
by: Peng Xu, et al.
Published: (2017-10-01)