Ablation of NK Cell Function During Tumor Growth Favors Type 2-Associated Macrophages, Leading to Suppressed CTL Generation
Several reports describe regulatory interactions between NK cells and CTLs. We addressed the issue of NK participation in the early anti-tumor defense by inoculating α-ASGM-1 treated mice with BW-Sp3 T lymphoma. Rejection of BW-Sp3 depends on strong CTL responses. Our results demonstrated that (i) N...
Main Authors: | Anja B. Geldhof, Jo A. van Ginderachter, Yuanqing Liu, Wim Noël, Patrick de Baetselier |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2003-01-01
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Series: | Clinical and Developmental Immunology |
Online Access: | http://dx.doi.org/10.1080/10446670310001626580 |
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