Impaired Differentiation of Highly Proliferative ICOS<sup>+</sup>-Tregs Is Involved in the Transition from Low to High Disease Activity in Systemic Lupus Erythematosus (SLE) Patients
Dysregulations in the differentiation of CD4<sup>+</sup>-regulatory-T-cells (Tregs) and CD4<sup>+</sup>-responder-T-cells (Tresps) are involved in the development of active systemic lupus erythematosus (SLE). Three differentiation pathways of highly proliferative inducible co...
Main Authors: | Florian Kälble, Lisa Wu, Hanns-Martin Lorenz, Martin Zeier, Matthias Schaier, Andrea Steinborn |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/17/9501 |
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