Impaired Differentiation of Highly Proliferative ICOS<sup>+</sup>-Tregs Is Involved in the Transition from Low to High Disease Activity in Systemic Lupus Erythematosus (SLE) Patients

Dysregulations in the differentiation of CD4<sup>+</sup>-regulatory-T-cells (Tregs) and CD4<sup>+</sup>-responder-T-cells (Tresps) are involved in the development of active systemic lupus erythematosus (SLE). Three differentiation pathways of highly proliferative inducible co...

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Bibliographic Details
Main Authors: Florian Kälble, Lisa Wu, Hanns-Martin Lorenz, Martin Zeier, Matthias Schaier, Andrea Steinborn
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/17/9501

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