Skin aging: Neuroendocrine challenge
Introduction. Skin is deeply affected by aging as all the organs do, including endocrine glands and neuroendocrine circuits. The anomalies of aging are connected to the internal aspects including hormonal panel mostly vitamin D status and glucocorticoid axes integrity, melatonin networking, thyroid...
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2020-03-01
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doaj-0c8b1fb8effd456c8bc7da39da6a71a22021-09-02T21:18:06ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2020-03-01671273010.37897/RMJ.2020.1.5Skin aging: Neuroendocrine challengeMara Carsote0Florica Sandru1Simona Elena Albu2Mihai Cristian Dumitrascu3Eugenia Petrova4Ana Valea5“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “C.I. Parhon” National Institute of Endocrinology, Bucharest, Romania “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Elias Emergency University Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Emergency University Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Emergency University Hospital, Bucharest, Romania “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “C.I. Parhon” National Institute of Endocrinology, Bucharest, Romania Clinical County Hospital, Cluj-Napoca, Romania; “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaIntroduction. Skin is deeply affected by aging as all the organs do, including endocrine glands and neuroendocrine circuits. The anomalies of aging are connected to the internal aspects including hormonal panel mostly vitamin D status and glucocorticoid axes integrity, melatonin networking, thyroid function, and catecholamines/serotonin release), state of health/illness, genetic background and bio-neuroendocrine/neurotransmitters pathways as well as immune defence. Moreover, external environment elements like sun exposure, radiations, pollution, physical, chemical and biological agents are consistent with internal mentioned aspects. Our purpose is to provide a mini-review regarding neuroendocrine and endocrine perspective of skin aging. Particular aspects on glucocorticoids, vitamin D and 5-hydroxytryptamine are pointed out. This is a narrative type of review. Skin is situated at the crossroad between intrinsic and extrinsic aging and the neuroendocrine approach is essential for understanding its time dependent changes.https://rmj.com.ro/articles/2020.1/RMJ_2020_1_Art-05.pdfskinendocrineneuroendocrineglucocorticoid5-hydroxytriptaminevitamin d |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mara Carsote Florica Sandru Simona Elena Albu Mihai Cristian Dumitrascu Eugenia Petrova Ana Valea |
spellingShingle |
Mara Carsote Florica Sandru Simona Elena Albu Mihai Cristian Dumitrascu Eugenia Petrova Ana Valea Skin aging: Neuroendocrine challenge Romanian Medical Journal skin endocrine neuroendocrine glucocorticoid 5-hydroxytriptamine vitamin d |
author_facet |
Mara Carsote Florica Sandru Simona Elena Albu Mihai Cristian Dumitrascu Eugenia Petrova Ana Valea |
author_sort |
Mara Carsote |
title |
Skin aging: Neuroendocrine challenge |
title_short |
Skin aging: Neuroendocrine challenge |
title_full |
Skin aging: Neuroendocrine challenge |
title_fullStr |
Skin aging: Neuroendocrine challenge |
title_full_unstemmed |
Skin aging: Neuroendocrine challenge |
title_sort |
skin aging: neuroendocrine challenge |
publisher |
Amaltea Medical Publishing House |
series |
Romanian Medical Journal |
issn |
1220-5478 2069-606X |
publishDate |
2020-03-01 |
description |
Introduction. Skin is deeply affected by aging as all the organs do, including endocrine glands and neuroendocrine circuits. The anomalies of aging are connected to the internal aspects including hormonal panel mostly vitamin D status and glucocorticoid axes integrity, melatonin networking, thyroid function, and catecholamines/serotonin release), state of health/illness, genetic background and bio-neuroendocrine/neurotransmitters pathways as well as immune defence. Moreover, external environment elements like sun exposure, radiations, pollution, physical, chemical and biological agents are consistent with internal mentioned aspects. Our purpose is to provide a mini-review regarding neuroendocrine and endocrine perspective of skin aging. Particular aspects on glucocorticoids, vitamin D and 5-hydroxytryptamine are pointed out. This is a narrative type of review. Skin is situated at the crossroad between intrinsic and extrinsic aging and the neuroendocrine approach is essential for understanding its time dependent changes. |
topic |
skin endocrine neuroendocrine glucocorticoid 5-hydroxytriptamine vitamin d |
url |
https://rmj.com.ro/articles/2020.1/RMJ_2020_1_Art-05.pdf |
work_keys_str_mv |
AT maracarsote skinagingneuroendocrinechallenge AT floricasandru skinagingneuroendocrinechallenge AT simonaelenaalbu skinagingneuroendocrinechallenge AT mihaicristiandumitrascu skinagingneuroendocrinechallenge AT eugeniapetrova skinagingneuroendocrinechallenge AT anavalea skinagingneuroendocrinechallenge |
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