Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors

<p>Abstract</p> <p>Background</p> <p>Development of neural networks requires that synapses are formed, eliminated and stabilized. At the neuromuscular junction (NMJ), agrin/MuSK signaling, by triggering downstream pathways, causes clustering and phosphorylation of posts...

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Bibliographic Details
Main Authors: Rüegg Markus A, Lin Shuo, Sadasivam Gayathri, Willmann Raffaella, Camilleri Alain A, Gesemann Matthias, Fuhrer Christian
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/8/46

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