From pulmonary embolism to chronic thromboembolic pulmonary hypertension: risk factors

• Main Authors: O. Ya. Vasiltseva, A. G. Edemskiy, D. S. Grankin, E. N. Kliver, A. M. Chernyavskiy
• Format: Article
• Language: Russian
• Published: Meshalkin National Medical Research Center 2021-09-01
• Series: Патология кровообращения и кардиохирургия
• Subjects: тромбоэмболия легочной артерии; хроническая тромбоэмболическая легочная гипертензия
• Online Access: http://journalmeshalkin.ru/index.php/heartjournal/article/view/980

<p>Chronic thromboembolic pulmonary hypertension is a long-term consequence of acute pulmonary embolism. Gradual obstruction of the pulmonary arteries and secondary changes in the pulmonary microcirculation over time cause progressive increases in pulmonary vascular resistance and pulmonary artery pressure that can result in severe right heart failure. This article provides an overview of pulmonary embolism and chronic thromboembolic pulmonary hypertension scientific literature and national guidelines. We focus on disease and recurrence risk factors and outline future directions of research to improve short- and long-term patient outcomes.</p><p>Received 17 January 2021. Revised 1 March 2021. Accepted 19 April 2021.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> The authors declare no conflicts of interests.</p><p><strong>Contribution of the authors</strong><br />Conception and study design: A.M. Chernyavskiy, A.G. Edemskiy, D.S. Grankin, E.N. Kliver<br />Drafting the article: O.Ya. Vasiltseva<br />Critical revision of the article: E.N. Kliver<br />Final approval of the version to be published: O.Ya. Vasiltseva, A.G. Edemskiy, D.S. Grankin, E.N. Kliver, A.M. Chernyavskiy</p>