The association between parity and spontaneous preterm birth: a population based study
Abstract Background Preterm birth is the leading cause of perinatal mortality and neonatal morbidity worldwide. Many factors have been associated with preterm birth, including parity. The aim of the present study was to investigate associations between parity and risk of spontaneous preterm birth. M...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
|
Series: | BMC Pregnancy and Childbirth |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12884-020-02940-w |
id |
doaj-0cac86eb20894ca7b06ffb91c0b2fcf4 |
---|---|
record_format |
Article |
spelling |
doaj-0cac86eb20894ca7b06ffb91c0b2fcf42020-11-25T03:23:31ZengBMCBMC Pregnancy and Childbirth1471-23932020-04-012011810.1186/s12884-020-02940-wThe association between parity and spontaneous preterm birth: a population based studyBouchra Koullali0Maud D. van Zijl1Brenda M. Kazemier2Martijn A. Oudijk3Ben W. J. Mol4Eva Pajkrt5Anita C. J. Ravelli6Department of Obstetrics and Gynecology, Amsterdam UMC, University of AmsterdamDepartment of Obstetrics and Gynecology, Amsterdam UMC, University of AmsterdamDepartment of Obstetrics and Gynecology, Amsterdam UMC, University of AmsterdamDepartment of Obstetrics and Gynecology, Amsterdam UMC, University of AmsterdamDepartment of Obstetrics and Gynecology, School of Medicine, Monash UniversityDepartment of Obstetrics and Gynecology, Amsterdam UMC, University of AmsterdamDepartment of Obstetrics and Gynecology, Amsterdam UMC, University of AmsterdamAbstract Background Preterm birth is the leading cause of perinatal mortality and neonatal morbidity worldwide. Many factors have been associated with preterm birth, including parity. The aim of the present study was to investigate associations between parity and risk of spontaneous preterm birth. Methods We conducted a retrospective study including live singleton births (≥22 weeks) of women with a first, second, third, fourth or fifth pregnancy in The Netherlands from 2010 through 2014. Our primary outcome was risk of spontaneous preterm birth < 37 weeks. Secondary outcomes were spontaneous preterm birth < 32 and < 28 weeks. Results We studied 802,119 pregnancies, including 30,237 pregnancies that ended spontaneously < 37 weeks. We identified an increased risk for spontaneous preterm birth < 37 weeks in nulliparous women (OR 1.95, 95% CI 1.89–2.00) and women in their fifth pregnancy (OR 1.26, 95% CI 1.13–1.41) compared to women in their second pregnancy. Similar results were seen for spontaneous preterm birth < 32 and < 28 weeks. Conclusion Our data show an independent association between nulliparity and spontaneous preterm birth < 37, < 32 and < 28 weeks. Furthermore, we observed an increased risk for spontaneous preterm birth in women in their fifth pregnancy, with highest risk for preterm birth at early gestational age.http://link.springer.com/article/10.1186/s12884-020-02940-wSpontaneous preterm birthParityNulliparityRisk factors |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bouchra Koullali Maud D. van Zijl Brenda M. Kazemier Martijn A. Oudijk Ben W. J. Mol Eva Pajkrt Anita C. J. Ravelli |
spellingShingle |
Bouchra Koullali Maud D. van Zijl Brenda M. Kazemier Martijn A. Oudijk Ben W. J. Mol Eva Pajkrt Anita C. J. Ravelli The association between parity and spontaneous preterm birth: a population based study BMC Pregnancy and Childbirth Spontaneous preterm birth Parity Nulliparity Risk factors |
author_facet |
Bouchra Koullali Maud D. van Zijl Brenda M. Kazemier Martijn A. Oudijk Ben W. J. Mol Eva Pajkrt Anita C. J. Ravelli |
author_sort |
Bouchra Koullali |
title |
The association between parity and spontaneous preterm birth: a population based study |
title_short |
The association between parity and spontaneous preterm birth: a population based study |
title_full |
The association between parity and spontaneous preterm birth: a population based study |
title_fullStr |
The association between parity and spontaneous preterm birth: a population based study |
title_full_unstemmed |
The association between parity and spontaneous preterm birth: a population based study |
title_sort |
association between parity and spontaneous preterm birth: a population based study |
publisher |
BMC |
series |
BMC Pregnancy and Childbirth |
issn |
1471-2393 |
publishDate |
2020-04-01 |
description |
Abstract Background Preterm birth is the leading cause of perinatal mortality and neonatal morbidity worldwide. Many factors have been associated with preterm birth, including parity. The aim of the present study was to investigate associations between parity and risk of spontaneous preterm birth. Methods We conducted a retrospective study including live singleton births (≥22 weeks) of women with a first, second, third, fourth or fifth pregnancy in The Netherlands from 2010 through 2014. Our primary outcome was risk of spontaneous preterm birth < 37 weeks. Secondary outcomes were spontaneous preterm birth < 32 and < 28 weeks. Results We studied 802,119 pregnancies, including 30,237 pregnancies that ended spontaneously < 37 weeks. We identified an increased risk for spontaneous preterm birth < 37 weeks in nulliparous women (OR 1.95, 95% CI 1.89–2.00) and women in their fifth pregnancy (OR 1.26, 95% CI 1.13–1.41) compared to women in their second pregnancy. Similar results were seen for spontaneous preterm birth < 32 and < 28 weeks. Conclusion Our data show an independent association between nulliparity and spontaneous preterm birth < 37, < 32 and < 28 weeks. Furthermore, we observed an increased risk for spontaneous preterm birth in women in their fifth pregnancy, with highest risk for preterm birth at early gestational age. |
topic |
Spontaneous preterm birth Parity Nulliparity Risk factors |
url |
http://link.springer.com/article/10.1186/s12884-020-02940-w |
work_keys_str_mv |
AT bouchrakoullali theassociationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT mauddvanzijl theassociationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT brendamkazemier theassociationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT martijnaoudijk theassociationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT benwjmol theassociationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT evapajkrt theassociationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT anitacjravelli theassociationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT bouchrakoullali associationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT mauddvanzijl associationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT brendamkazemier associationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT martijnaoudijk associationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT benwjmol associationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT evapajkrt associationbetweenparityandspontaneouspretermbirthapopulationbasedstudy AT anitacjravelli associationbetweenparityandspontaneouspretermbirthapopulationbasedstudy |
_version_ |
1724605906333728768 |