Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level

Accumulation of somatic mutations is critical for the transition of a normal cell to become cancerous. Mutations cause amino acid substitutions that change properties of proteins. However, it has not been studied as to what extent the composition and accordingly chemical properties of the cell prote...

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Bibliographic Details
Main Authors: Viktoriia Tsuber, Yunus Kadamov, Lars Brautigam, Ulrika Warpman Berglund, Thomas Helleday
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/7/3/49