A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India

Objective: To determine the prevalence of ABO and Rh blood groups based on the antigenic presence on the surface of red blood cells with respect to gender and calculate allele frequency of the blood groups. Globally, approximately 700 type red cell antigens have been identified till now. ABO and Rh...

Full description

Bibliographic Details
Main Authors: Satish Kumar, Purab Kalyan Modak, S Haroon Ali, S K Barpanda, Vimal Singh Gusain, Rupali Roy
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Journal of Family Medicine and Primary Care
Subjects:
Online Access:http://www.jfmpc.com/article.asp?issn=2249-4863;year=2018;volume=7;issue=1;spage=34;epage=38;aulast=Kumar
id doaj-0cba5ecd66974c8b8752b5df8e7dc16f
record_format Article
spelling doaj-0cba5ecd66974c8b8752b5df8e7dc16f2020-11-24T23:09:04ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632018-01-0171343810.4103/jfmpc.jfmpc_252_17A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, IndiaSatish KumarPurab Kalyan ModakS Haroon AliS K BarpandaVimal Singh GusainRupali RoyObjective: To determine the prevalence of ABO and Rh blood groups based on the antigenic presence on the surface of red blood cells with respect to gender and calculate allele frequency of the blood groups. Globally, approximately 700 type red cell antigens have been identified till now. ABO and Rh blood groups play an important role in the process of blood transfusion, resolving certain medicolegal issues, parental testing, and various genetic studies. Methods: This study was conducted in H.N.B. Base Hospital, Srinagar, Uttarakhand, from January 2012 to December 2016. Relevant data of blood donors were collected from blood bank department of the hospital. Blood grouping was conducted using commercially available standard monoclonal antisera applying test tube and column agglutination techniques. Results: Out of 9883 individuals, 9333 (92.4%) were males and 750 (7.6%) were female individuals. The most common blood group found was B (31.68%) and least common being AB (11.70%). The prevalence of Rhesus positive and negative distribution in the present studied population was found as 93.51% and 6.49%, respectively. Overall, male ABO group pattern found was shown by formula B > A > O > AB which was similar among Rh-positive male individuals while Rh-negative males' pattern was found as A > B = O > AB. In females, ABO group pattern was B > O > A > AB which was similar to Rh-positive female pattern while differs in Rh negative. The estimated allele frequencies were found as 0.2403, 0.2475, and 0.5122 for IA (p), IB (q), and IO (r), respectively. Conclusion: The most common blood group found among the Gharwali donors was B positive while the least common was AB negative, which plays an important contribution for making government policies to develop National Health Program.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2018;volume=7;issue=1;spage=34;epage=38;aulast=KumarsABO and Rh blood groupallele frequencyblood donor
collection DOAJ
language English
format Article
sources DOAJ
author Satish Kumar
Purab Kalyan Modak
S Haroon Ali
S K Barpanda
Vimal Singh Gusain
Rupali Roy
spellingShingle Satish Kumar
Purab Kalyan Modak
S Haroon Ali
S K Barpanda
Vimal Singh Gusain
Rupali Roy
A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India
Journal of Family Medicine and Primary Care
sABO and Rh blood group
allele frequency
blood donor
author_facet Satish Kumar
Purab Kalyan Modak
S Haroon Ali
S K Barpanda
Vimal Singh Gusain
Rupali Roy
author_sort Satish Kumar
title A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India
title_short A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India
title_full A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India
title_fullStr A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India
title_full_unstemmed A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India
title_sort retrospective study: abo and rh phenotype blood group distribution among blood donors in h.n.b. base hospital, srinagar, uttarakhand, india
publisher Wolters Kluwer Medknow Publications
series Journal of Family Medicine and Primary Care
issn 2249-4863
publishDate 2018-01-01
description Objective: To determine the prevalence of ABO and Rh blood groups based on the antigenic presence on the surface of red blood cells with respect to gender and calculate allele frequency of the blood groups. Globally, approximately 700 type red cell antigens have been identified till now. ABO and Rh blood groups play an important role in the process of blood transfusion, resolving certain medicolegal issues, parental testing, and various genetic studies. Methods: This study was conducted in H.N.B. Base Hospital, Srinagar, Uttarakhand, from January 2012 to December 2016. Relevant data of blood donors were collected from blood bank department of the hospital. Blood grouping was conducted using commercially available standard monoclonal antisera applying test tube and column agglutination techniques. Results: Out of 9883 individuals, 9333 (92.4%) were males and 750 (7.6%) were female individuals. The most common blood group found was B (31.68%) and least common being AB (11.70%). The prevalence of Rhesus positive and negative distribution in the present studied population was found as 93.51% and 6.49%, respectively. Overall, male ABO group pattern found was shown by formula B > A > O > AB which was similar among Rh-positive male individuals while Rh-negative males' pattern was found as A > B = O > AB. In females, ABO group pattern was B > O > A > AB which was similar to Rh-positive female pattern while differs in Rh negative. The estimated allele frequencies were found as 0.2403, 0.2475, and 0.5122 for IA (p), IB (q), and IO (r), respectively. Conclusion: The most common blood group found among the Gharwali donors was B positive while the least common was AB negative, which plays an important contribution for making government policies to develop National Health Program.
topic sABO and Rh blood group
allele frequency
blood donor
url http://www.jfmpc.com/article.asp?issn=2249-4863;year=2018;volume=7;issue=1;spage=34;epage=38;aulast=Kumar
work_keys_str_mv AT satishkumar aretrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT purabkalyanmodak aretrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT sharoonali aretrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT skbarpanda aretrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT vimalsinghgusain aretrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT rupaliroy aretrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT satishkumar retrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT purabkalyanmodak retrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT sharoonali retrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT skbarpanda retrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT vimalsinghgusain retrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
AT rupaliroy retrospectivestudyaboandrhphenotypebloodgroupdistributionamongblooddonorsinhnbbasehospitalsrinagaruttarakhandindia
_version_ 1725611700813561856