Is the sigma-1 receptor a potential pharmacological target for cardiac pathologies? A systematic review

Sigma-1 receptors are ligand-regulated chaperone proteins, involved in several cellular mechanisms. The aim of this systematic review was to examine the effects that the sigma-1 receptor has on the cardiovascular system. The interaction targets and proposed mechanisms of action of sigma-1 receptors...

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Bibliographic Details
Main Authors: Rebecca Lewis, Jiaqi Li, Peter J McCormick, Christopher L-H Huang, Kamalan Jeevaratnam
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:International Journal of Cardiology: Heart & Vasculature
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906719301988