ART-Treated Patients Exhibit an Adaptive Immune Response against the HFVAC Peptides, a Potential HIV-1 Therapeutic Vaccine (Provir/Latitude45 Study)

ART-Treated Patients Exhibit an Adaptive Immune Response against the HFVAC Peptides, a Potential HIV-1 Therapeutic Vaccine (Provir/Latitude45 Study)

We proposed a new HIV-1 therapeutic vaccine based on conserved cytotoxic T lymphocyte (CTL) epitopes of archived HIV-1 DNA according to their affinity to the dominant HLA-A and -B alleles of the population investigated. Our proposal (Hla Fitted VAC, HFVAC) was composed of 15 peptides originating fro...

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Bibliographic Details
Main Authors: Hervé Fleury, Sabrina Caldato, Patricia Recordon-Pinson, Patricia Thebault, Gwenda-Line Guidicelli, Mojgan Hessamfar, Philippe Morlat, Fabrice Bonnet, Jonathan Visentin
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Viruses
Subjects:
HIV-1
vaccine
HFVAC
CTL epitopes
archived proviral DNA
HLA I alleles
Online Access:https://www.mdpi.com/1999-4915/12/11/1256

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