Automated cleaning and pre-processing of immunoglobulin gene sequences from high-throughput sequencing
High throughput sequencing (HTS) yields tens of thousands to millions of sequences that require a large amount of pre-processing work to clean various artifacts. Such cleaning cannot be performed manually. Existing programs are not suitable for immunoglobulin (Ig) genes, which are variable and often...
Main Authors: | Miri eMichaeli, Hila eNoga, Hilla eTabibian-Keissar, Iris eBarshack, Ramit eMehr |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-12-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00386/full |
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