Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamides

Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamides

Schiff base derivatives of benzothiazole 2a–e have been synthesized by reacting with substituted 2-aminobenzothiazole 1a–e and different substituted benzaldehydes 5a–e. The obtained Schiff bases reaction with NaBH4 has afforded the corresponding some novel amines 3a–e. The condensation of amines wit...

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Bibliographic Details
Main Authors: H.C. Sakarya, K. Görgün, C. Öğretir
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Arabian Journal of Chemistry
Subjects:
Benzothiazole
Benzothiazole-2-yl-amide
Schiff base
Reduction
Acylation
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535212000366
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spelling doaj-0d09a13d6f9a40ec87c2ac2d70a00a052020-11-24T21:06:07ZengElsevierArabian Journal of Chemistry1878-53522016-11-019S2S1314S131910.1016/j.arabjc.2012.02.008Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamidesH.C. SakaryaK. GörgünC. ÖğretirSchiff base derivatives of benzothiazole 2a–e have been synthesized by reacting with substituted 2-aminobenzothiazole 1a–e and different substituted benzaldehydes 5a–e. The obtained Schiff bases reaction with NaBH4 has afforded the corresponding some novel amines 3a–e. The condensation of amines with chloroacetylchloride leads to novel amide derivatives 4a–e. The structures of the synthesized compounds are characterized by elemental analysis, IR, MS, 1H NMR and 13C NMR.http://www.sciencedirect.com/science/article/pii/S1878535212000366BenzothiazoleBenzothiazole-2-yl-amideSchiff baseReductionAcylation
collection DOAJ
language English
format Article
sources DOAJ
author H.C. Sakarya
K. Görgün
C. Öğretir
spellingShingle H.C. Sakarya
K. Görgün
C. Öğretir
Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamides
Arabian Journal of Chemistry
Benzothiazole
Benzothiazole-2-yl-amide
Schiff base
Reduction
Acylation
author_facet H.C. Sakarya
K. Görgün
C. Öğretir
author_sort H.C. Sakarya
title Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamides
title_short Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamides
title_full Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamides
title_fullStr Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamides
title_full_unstemmed Synthesis and characterization of novel substituted N-benzothiazole-2-yl-acetamides
title_sort synthesis and characterization of novel substituted n-benzothiazole-2-yl-acetamides
publisher Elsevier
series Arabian Journal of Chemistry
issn 1878-5352
publishDate 2016-11-01
description Schiff base derivatives of benzothiazole 2a–e have been synthesized by reacting with substituted 2-aminobenzothiazole 1a–e and different substituted benzaldehydes 5a–e. The obtained Schiff bases reaction with NaBH4 has afforded the corresponding some novel amines 3a–e. The condensation of amines with chloroacetylchloride leads to novel amide derivatives 4a–e. The structures of the synthesized compounds are characterized by elemental analysis, IR, MS, 1H NMR and 13C NMR.
topic Benzothiazole
Benzothiazole-2-yl-amide
Schiff base
Reduction
Acylation
url http://www.sciencedirect.com/science/article/pii/S1878535212000366
work_keys_str_mv AT hcsakarya synthesisandcharacterizationofnovelsubstitutednbenzothiazole2ylacetamides
AT kgorgun synthesisandcharacterizationofnovelsubstitutednbenzothiazole2ylacetamides
AT cogretir synthesisandcharacterizationofnovelsubstitutednbenzothiazole2ylacetamides
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