The effect of combinated treatment of a metastatic HER2-positive stomach cancer

Trastuzumab in combination with standard chemotherapy has shown its effectiveness in treating HER2-positive metastatic gastric cancer. The median overall survival in its application is 16,8 months compared with 11,8 months when chemotherapy using alone. Authors demonstrate the case of the successful...

Full description

Bibliographic Details
Main Authors: R A Khvastunov, A Yu Nenarokomov, S E Tolstopiatov, K G Babina
Format: Article
Language:Russian
Published: IP Habib O.N. 2014-12-01
Series:Современная онкология
Subjects:
Online Access:https://modernonco.orscience.ru/1815-1434/article/view/26960
id doaj-0d27733eafb24e0895585d54f7da7d33
record_format Article
spelling doaj-0d27733eafb24e0895585d54f7da7d332020-11-25T03:23:24ZrusIP Habib O.N.Современная онкология1815-14341815-14422014-12-01164212324180The effect of combinated treatment of a metastatic HER2-positive stomach cancerR A Khvastunov0A Yu Nenarokomov1S E Tolstopiatov2K G Babina3Volgograd State medical university (400131, pl. Pavshikh Bortsov 1a, Volgograd, Russia); Volgograd regional clinical oncologic dispensary №1Volgograd State medical university (400131, pl. Pavshikh Bortsov 1a, Volgograd, Russia)Volgograd State medical university (400131, pl. Pavshikh Bortsov 1a, Volgograd, Russia)Volgograd regional clinical oncologic dispensary №3, VolzhskyTrastuzumab in combination with standard chemotherapy has shown its effectiveness in treating HER2-positive metastatic gastric cancer. The median overall survival in its application is 16,8 months compared with 11,8 months when chemotherapy using alone. Authors demonstrate the case of the successful using trastuzumab in the third line chemotherapy in patients with primary unresectable metastatic gastric cancer. As a result of the 12 courses of therapy almost complete tumor regression was achieved. It allowed to perform R0- gastrectomy. Currently, the patient continues trastuzumab treating in monoregime.https://modernonco.orscience.ru/1815-1434/article/view/26960her2-povitive gastric cancertrastuzumabtarget therapy
collection DOAJ
language Russian
format Article
sources DOAJ
author R A Khvastunov
A Yu Nenarokomov
S E Tolstopiatov
K G Babina
spellingShingle R A Khvastunov
A Yu Nenarokomov
S E Tolstopiatov
K G Babina
The effect of combinated treatment of a metastatic HER2-positive stomach cancer
Современная онкология
her2-povitive gastric cancer
trastuzumab
target therapy
author_facet R A Khvastunov
A Yu Nenarokomov
S E Tolstopiatov
K G Babina
author_sort R A Khvastunov
title The effect of combinated treatment of a metastatic HER2-positive stomach cancer
title_short The effect of combinated treatment of a metastatic HER2-positive stomach cancer
title_full The effect of combinated treatment of a metastatic HER2-positive stomach cancer
title_fullStr The effect of combinated treatment of a metastatic HER2-positive stomach cancer
title_full_unstemmed The effect of combinated treatment of a metastatic HER2-positive stomach cancer
title_sort effect of combinated treatment of a metastatic her2-positive stomach cancer
publisher IP Habib O.N.
series Современная онкология
issn 1815-1434
1815-1442
publishDate 2014-12-01
description Trastuzumab in combination with standard chemotherapy has shown its effectiveness in treating HER2-positive metastatic gastric cancer. The median overall survival in its application is 16,8 months compared with 11,8 months when chemotherapy using alone. Authors demonstrate the case of the successful using trastuzumab in the third line chemotherapy in patients with primary unresectable metastatic gastric cancer. As a result of the 12 courses of therapy almost complete tumor regression was achieved. It allowed to perform R0- gastrectomy. Currently, the patient continues trastuzumab treating in monoregime.
topic her2-povitive gastric cancer
trastuzumab
target therapy
url https://modernonco.orscience.ru/1815-1434/article/view/26960
work_keys_str_mv AT rakhvastunov theeffectofcombinatedtreatmentofametastaticher2positivestomachcancer
AT ayunenarokomov theeffectofcombinatedtreatmentofametastaticher2positivestomachcancer
AT setolstopiatov theeffectofcombinatedtreatmentofametastaticher2positivestomachcancer
AT kgbabina theeffectofcombinatedtreatmentofametastaticher2positivestomachcancer
AT rakhvastunov effectofcombinatedtreatmentofametastaticher2positivestomachcancer
AT ayunenarokomov effectofcombinatedtreatmentofametastaticher2positivestomachcancer
AT setolstopiatov effectofcombinatedtreatmentofametastaticher2positivestomachcancer
AT kgbabina effectofcombinatedtreatmentofametastaticher2positivestomachcancer
_version_ 1724606481461936128