Membrane alterations induced by nonstructural proteins of human norovirus.
Human noroviruses (huNoV) are the most frequent cause of non-bacterial acute gastroenteritis worldwide, particularly genogroup II genotype 4 (GII.4) variants. The viral nonstructural (NS) proteins encoded by the ORF1 polyprotein induce vesical clusters harboring the viral replication sites. Little i...
Main Authors: | Sylvie Y Doerflinger, Mirko Cortese, Inés Romero-Brey, Zach Menne, Thibault Tubiana, Christian Schenk, Peter A White, Ralf Bartenschlager, Stéphane Bressanelli, Grant S Hansman, Volker Lohmann |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-10-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC5678787?pdf=render |
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