Review: Progress in the management of paraneoplastic neurological disorders

Review: Progress in the management of paraneoplastic neurological disorders

Paraneoplastic neurological disorders (PNDs) are a rare and diverse group of neurological conditions that can involve any part of the nervous system. Diagnosis is facilitated by finding well-recognized autoantibodies directed against neural antigens in the sera and the cerebrospinal fluid. Identifyi...

Full description

Bibliographic Details
Main Authors: Hamid Sadeghian, Steven Vernino
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756285609349521
id doaj-0d473eec3d1c4e57bd303d4b062a93cc
record_format Article
spelling doaj-0d473eec3d1c4e57bd303d4b062a93cc2020-11-25T03:49:53ZengSAGE PublishingTherapeutic Advances in Neurological Disorders1756-28562010-01-01310.1177/1756285609349521Review: Progress in the management of paraneoplastic neurological disordersHamid SadeghianSteven VerninoParaneoplastic neurological disorders (PNDs) are a rare and diverse group of neurological conditions that can involve any part of the nervous system. Diagnosis is facilitated by finding well-recognized autoantibodies directed against neural antigens in the sera and the cerebrospinal fluid. Identifying and eliminating the underlying malignancy is the mainstay of treatment. Immunomodulatory treatment is gaining more acceptance especially, where a malignancy could not be identified, oncology treatment is completed, or along with cancer treatment. Literature review shows only a handful of systematic prospective case series. Multicenter, prospective controlled clinical trials are needed for future therapeutic advances.https://doi.org/10.1177/1756285609349521
collection DOAJ
language English
format Article
sources DOAJ
author Hamid Sadeghian
Steven Vernino
spellingShingle Hamid Sadeghian
Steven Vernino
Review: Progress in the management of paraneoplastic neurological disorders
Therapeutic Advances in Neurological Disorders
author_facet Hamid Sadeghian
Steven Vernino
author_sort Hamid Sadeghian
title Review: Progress in the management of paraneoplastic neurological disorders
title_short Review: Progress in the management of paraneoplastic neurological disorders
title_full Review: Progress in the management of paraneoplastic neurological disorders
title_fullStr Review: Progress in the management of paraneoplastic neurological disorders
title_full_unstemmed Review: Progress in the management of paraneoplastic neurological disorders
title_sort review: progress in the management of paraneoplastic neurological disorders
publisher SAGE Publishing
series Therapeutic Advances in Neurological Disorders
issn 1756-2856
publishDate 2010-01-01
description Paraneoplastic neurological disorders (PNDs) are a rare and diverse group of neurological conditions that can involve any part of the nervous system. Diagnosis is facilitated by finding well-recognized autoantibodies directed against neural antigens in the sera and the cerebrospinal fluid. Identifying and eliminating the underlying malignancy is the mainstay of treatment. Immunomodulatory treatment is gaining more acceptance especially, where a malignancy could not be identified, oncology treatment is completed, or along with cancer treatment. Literature review shows only a handful of systematic prospective case series. Multicenter, prospective controlled clinical trials are needed for future therapeutic advances.
url https://doi.org/10.1177/1756285609349521
work_keys_str_mv AT hamidsadeghian reviewprogressinthemanagementofparaneoplasticneurologicaldisorders
AT stevenvernino reviewprogressinthemanagementofparaneoplasticneurologicaldisorders
_version_ 1724493517718290432

Similar Items