Laryngeal carcinoma presenting as polymyositis: A paraneoplastic syndrome

• Main Authors: Ritesh Sahu, Bhanu Pratap Rathaur, Tejendra Sukdeo Chaudhari, Rakesh Shukla, Kiran Preet Malhotra
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2016-01-01
• Series: Annals of Indian Academy of Neurology
• Subjects: Laryngeal carcinoma; muscle biopsy; polymyositis
• Online Access: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=1;spage=150;epage=151;aulast=Sahu

Laryngeal carcinoma is rarely associated with paraneoplastic syndrome. Inflammatory myopathy presenting as paraneoplastic event is commonly associated with carcinomas of ovary, lung, pancreas, stomach, colorectal, and non-Hodgkin′s lymphoma. We report a case of elderly male, who presented with proximal muscle weakness and found to be associated with laryngeal carcinoma. Diagnosis of polymyositis (PM) was confirmed based on clinical features, laboratory test, and muscle biopsy. Exclusion of other commonly associated malignancies was done. This patient improved gradually after 6 months of immunosuppressive therapy and management of underlying cancer.