Inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentation

Respiratory failure in the premature newborn may be complicated by pulmonary hypertension (PAH) that does not always respond to conventional therapies. Conventional therapy for PAH involves: respiratory support, surfactant administration, sedation and / or muscle relaxation and inotropic agents in t...

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Main Authors: Mihaela Demetrian, Georgeta Grecu, Andreea Vidru, Andreea Calomfirescu-Avramescu, Alina Ciuca, Anca Panaitescu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2020-09-01
Series:Romanian Journal of Pediatrics
Subjects:
Online Access:https://rjp.com.ro/articles/2020.3/RJP_2020_3_EN_Art-09.pdf
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spelling doaj-0d49f131aac7420d9b4e908e22db9f452021-09-02T21:33:08ZengAmaltea Medical Publishing HouseRomanian Journal of Pediatrics1454-03982069-61752020-09-0169325125510.37897/RJP.2020.3.9Inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentationMihaela Demetrian0Georgeta Grecu1Andreea Vidru2Andreea Calomfirescu-Avramescu3Alina Ciuca4Anca Panaitescu5”Filantropia” Clinical Hospital, Bucharest, Romania”Filantropia” Clinical Hospital, Bucharest, Romania”Filantropia” Clinical Hospital, Bucharest, Romania”Filantropia” Clinical Hospital, Bucharest, Romania“Grigore Alexandrescu“ Children’s Emergency Clinical Hospital, Bucharest, Romania “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaRespiratory failure in the premature newborn may be complicated by pulmonary hypertension (PAH) that does not always respond to conventional therapies. Conventional therapy for PAH involves: respiratory support, surfactant administration, sedation and / or muscle relaxation and inotropic agents in the most premature patients. Our experience in nitric oxide therapy in premature infants under 32 weeks dates back approximately 5 years. There were 7 cases of premature infants with respiratory failure who did not respond to conventional methods of therapy. We will present three case reports with hypoxic respiratory failure and severe pulmonary hypertension that responded favorably to nitric oxide therapy.https://rjp.com.ro/articles/2020.3/RJP_2020_3_EN_Art-09.pdfpremature infantspulmonary hypertensioninhaled nitric oxide
collection DOAJ
language English
format Article
sources DOAJ
author Mihaela Demetrian
Georgeta Grecu
Andreea Vidru
Andreea Calomfirescu-Avramescu
Alina Ciuca
Anca Panaitescu
spellingShingle Mihaela Demetrian
Georgeta Grecu
Andreea Vidru
Andreea Calomfirescu-Avramescu
Alina Ciuca
Anca Panaitescu
Inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentation
Romanian Journal of Pediatrics
premature infants
pulmonary hypertension
inhaled nitric oxide
author_facet Mihaela Demetrian
Georgeta Grecu
Andreea Vidru
Andreea Calomfirescu-Avramescu
Alina Ciuca
Anca Panaitescu
author_sort Mihaela Demetrian
title Inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentation
title_short Inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentation
title_full Inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentation
title_fullStr Inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentation
title_full_unstemmed Inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentation
title_sort inhaled nitric oxide theraphy in preterm infants with severe pulmonary distress syndrome – cases presentation
publisher Amaltea Medical Publishing House
series Romanian Journal of Pediatrics
issn 1454-0398
2069-6175
publishDate 2020-09-01
description Respiratory failure in the premature newborn may be complicated by pulmonary hypertension (PAH) that does not always respond to conventional therapies. Conventional therapy for PAH involves: respiratory support, surfactant administration, sedation and / or muscle relaxation and inotropic agents in the most premature patients. Our experience in nitric oxide therapy in premature infants under 32 weeks dates back approximately 5 years. There were 7 cases of premature infants with respiratory failure who did not respond to conventional methods of therapy. We will present three case reports with hypoxic respiratory failure and severe pulmonary hypertension that responded favorably to nitric oxide therapy.
topic premature infants
pulmonary hypertension
inhaled nitric oxide
url https://rjp.com.ro/articles/2020.3/RJP_2020_3_EN_Art-09.pdf
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