Computed tomographic evaluation of cleft palate in one-day-old puppies

• Main Authors: Filip Pankowski, Sławomir Paśko, Andrzej Max, Bartłomiej Szal, Małgorzata Dzierzęcka, Joanna Gruszczyńska, Paweł Szaro, Marek Gołębiowski, Bartłomiej Jan Bartyzel
• Format: Article
• Language: English
• Published: BMC 2018-10-01
• Series: BMC Veterinary Research
• Subjects: 3D modeling; Anatomy; Dogs; Newborn; Radiology; STL
• Online Access: http://link.springer.com/article/10.1186/s12917-018-1642-6

Abstract Background Cleft palate is a birth defect characterized by a lack of fusion between structures forming the palate. Causes include a multitude of factors, both genetic and environmental. Computed tomography (CT) is widely used to evaluate morphological features and diagnose head disorders in adult dogs. However, there is less data about its use in neonatal dogs. The purpose of this study was to perform CT evaluation of palatal defects in one-day-old puppies and to present a novel approach of 3D modeling in terms of cleft palate assessment. Results Macroscopic and CT examinations were performed in 23 stillborn or euthanized purebred newborn puppies. On the basis of CT data, a 3D model was prepared and the cleft surface area was then calculated. A multi-stage approach, which utilised software such as 3D Slicer and Blender, was applied. Palatal defects were found in ten dogs, of which five had cleft palate, three had bilateral cleft lip and palate, one had a unilateral cleft lip and palate and one had a unilateral cleft lip. The surface area of the clefts ranged from 31 to 213 mm2, which made up respectfully 11 to 63% of the total surface area of the palate. No abnormalities were found in thirteen dogs and they made up the control group. Conclusions Computed tomography and 3D modeling were very effective in evaluation of palatal disorders in newborn dogs. 3D models adapted to the natural curvature of the palate were created and more precise data was obtained. Morphological characteristics, CT findings and advanced image analysis of cleft palate in neonates obtained from these models increase the knowledge about this malformation in dogs.