Protecting-Group-Free Synthesis of 2-Deoxy-Aza-Sugars
The protecting-group-free asymmetric synthesis of 1,2,4-trideoxy-1,4-imino-L-xylitol is readily achieved in five steps from 2-deoxy-D-ribose and with an overall yield of 48%. Key in this synthesis is the application of our recently developed Vasella-reductive amination and carbamate annulation metho...
Main Authors: | Mattie Simon Maria Timmer, Bridget Louise Stocker, Emma Marie Dangerfield, Catherine Heather Plunkett |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2009-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/14/12/5298/ |
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