Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in India
Background: Metabolic syndrome is characterized by hypertension, dyslipidemia, central obesity, glucose intolerance, insulin resistance. Thyroid hormone acts as general pacemaker, accelerating metabolic process and may be associated with metabolic syndrome. There is no information available in liter...
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Manipal College of Medical Sciences, Pokhara
2021-10-01
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doaj-0d993f33b17d4fdc8af3fe7d8fbc99612021-10-01T16:37:39ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762021-10-0112104750https://doi.org/10.3126/ajms.v12i10.38313Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in IndiaRitu Gupta 0https://orcid.org/0000-0003-4937-5412Akhil K Vijayan 1https://orcid.org/0000-0001-9127-0652Sushma Choudhary 2https://orcid.org/0000-0002-3724-758XProfessor and Head, Department of Medicine, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India Postgraduate Resident, Department of Medicine, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India Assistant Professor, Department of Medicine, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India Background: Metabolic syndrome is characterized by hypertension, dyslipidemia, central obesity, glucose intolerance, insulin resistance. Thyroid hormone acts as general pacemaker, accelerating metabolic process and may be associated with metabolic syndrome. There is no information available in literature regarding the prevalence and association of thyroid dysfunction in metabolic syndrome in this central region of the country. Aims and Objective: To estimate the prevalence of thyroid dysfunction in patients of metabolic syndrome. Materials and Methods: It is a duration based prospective cross sectional study including 200 patients of metabolic syndrome. A detailed history, clinical examination and relevant investigations including serum Free T4 (FT4), Free T3 (FT3), Thyroid Stimulating Hormone (TSH) were done. Range, frequencies, percentage, mean, standard deviation and P value were calculated. P value of < 0.05 was taken as significant. Results: Prevalence of thyroid dysfunction in metabolic syndrome patients was 28.5%. Prevalence of subclinical and overt hypothyroidism was 18.5% and 8.5% respectively. In patients with both metabolic syndrome and thyroid dysfunction, most common components associated are diabetes mellitus and hypertriglyceridemia. Conclusion: Thyroid dysfunction is significantly common in metabolic syndrome patients. It should be aggressively detected and treated in these patients for better outcome.https://www.nepjol.info/index.php/AJMS/article/view/38313metabolic syndrome; thyroid dysfunction; hypothyroidism; subclinical hypothyroidism; hyperthyroidism; diabetes mellitus. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ritu Gupta Akhil K Vijayan Sushma Choudhary |
spellingShingle |
Ritu Gupta Akhil K Vijayan Sushma Choudhary Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in India Asian Journal of Medical Sciences metabolic syndrome; thyroid dysfunction; hypothyroidism; subclinical hypothyroidism; hyperthyroidism; diabetes mellitus. |
author_facet |
Ritu Gupta Akhil K Vijayan Sushma Choudhary |
author_sort |
Ritu Gupta |
title |
Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in India |
title_short |
Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in India |
title_full |
Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in India |
title_fullStr |
Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in India |
title_full_unstemmed |
Thyroid dysfunction in patients of metabolic syndrome: A study from a tertiary care center in India |
title_sort |
thyroid dysfunction in patients of metabolic syndrome: a study from a tertiary care center in india |
publisher |
Manipal College of Medical Sciences, Pokhara |
series |
Asian Journal of Medical Sciences |
issn |
2467-9100 2091-0576 |
publishDate |
2021-10-01 |
description |
Background: Metabolic syndrome is characterized by hypertension, dyslipidemia, central obesity, glucose intolerance, insulin resistance. Thyroid hormone acts as general pacemaker, accelerating metabolic process and may be associated with metabolic syndrome. There is no information available in literature regarding the prevalence and association of thyroid dysfunction in metabolic syndrome in this central region of the country.
Aims and Objective: To estimate the prevalence of thyroid dysfunction in patients of metabolic syndrome.
Materials and Methods: It is a duration based prospective cross sectional study including 200 patients of metabolic syndrome. A detailed history, clinical examination and relevant investigations including serum Free T4 (FT4), Free T3 (FT3), Thyroid Stimulating Hormone (TSH) were done. Range, frequencies, percentage, mean, standard deviation and P value were calculated. P value of < 0.05 was taken as significant.
Results: Prevalence of thyroid dysfunction in metabolic syndrome patients was 28.5%. Prevalence of subclinical and overt hypothyroidism was 18.5% and 8.5% respectively. In patients with both metabolic syndrome and thyroid dysfunction, most common components associated are diabetes mellitus and hypertriglyceridemia.
Conclusion: Thyroid dysfunction is significantly common in metabolic syndrome patients. It should be aggressively detected and treated in these patients for better outcome. |
topic |
metabolic syndrome; thyroid dysfunction; hypothyroidism; subclinical hypothyroidism; hyperthyroidism; diabetes mellitus. |
url |
https://www.nepjol.info/index.php/AJMS/article/view/38313 |
work_keys_str_mv |
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