Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner
Neural crest progenitors are specified through the modulation of several signaling pathways, among which the activation of Wnt/β-catenin signaling by Wnt8 is especially critical. Glycoproteins of the Dickkopf (Dkk) family are important modulators of Wnt signaling acting primarily as Wnt antagonists....
Main Authors: | Arun Devotta, Chang-Soo Hong, Jean-Pierre Saint-Jeannet |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/34404 |
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