The mosquito holobiont: fresh insight into mosquito-microbiota interactions
Abstract The holobiont concept was first developed for coral ecosystems but has been extended to multiple organisms, including plants and other animals. Studies on insect-associated microbial communities have produced strong evidence that symbiotic bacteria play a major role in host biology. However...
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doaj-0e33e7d94bb6426087cef6b9b808e9642020-11-24T21:04:11ZengBMCMicrobiome2049-26182018-03-016111710.1186/s40168-018-0435-2The mosquito holobiont: fresh insight into mosquito-microbiota interactionsMorgane Guégan0Karima Zouache1Colin Démichel2Guillaume Minard3Van Tran Van4Patrick Potier5Patrick Mavingui6Claire Valiente Moro7Université de LyonUniversité de LyonUniversité de LyonUniversité de LyonUniversité de LyonUniversité de LyonUniversité de LyonUniversité de LyonAbstract The holobiont concept was first developed for coral ecosystems but has been extended to multiple organisms, including plants and other animals. Studies on insect-associated microbial communities have produced strong evidence that symbiotic bacteria play a major role in host biology. However, the understanding of these symbiotic relationships has mainly been limited to phytophagous insects, while the role of host-associated microbiota in haematophagous insect vectors remains largely unexplored. Mosquitoes are a major global public health concern, with a concomitant increase in people at risk of infection. The global emergence and re-emergence of mosquito-borne diseases has led many researchers to study both the mosquito host and its associated microbiota. Although most of these studies have been descriptive, they have led to a broad description of the bacterial communities hosted by mosquito populations. This review describes key advances and progress in the field of the mosquito microbiota research while also encompassing other microbes and the environmental factors driving their composition and diversity. The discussion includes recent findings on the microbiota functional roles and underlines their interactions with the host biology and pathogen transmission. Insight into the ecology of multipartite interactions, we consider that conferring the term holobiont to the mosquito and its microbiota is useful to get a comprehensive understanding of the vector pathosystem functioning so as to be able to develop innovative and efficient novel vector control strategies.http://link.springer.com/article/10.1186/s40168-018-0435-2MosquitoPan-microbiotaMultiple interactionsSymbiosisAdaptationPathogen transmission |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Morgane Guégan Karima Zouache Colin Démichel Guillaume Minard Van Tran Van Patrick Potier Patrick Mavingui Claire Valiente Moro |
spellingShingle |
Morgane Guégan Karima Zouache Colin Démichel Guillaume Minard Van Tran Van Patrick Potier Patrick Mavingui Claire Valiente Moro The mosquito holobiont: fresh insight into mosquito-microbiota interactions Microbiome Mosquito Pan-microbiota Multiple interactions Symbiosis Adaptation Pathogen transmission |
author_facet |
Morgane Guégan Karima Zouache Colin Démichel Guillaume Minard Van Tran Van Patrick Potier Patrick Mavingui Claire Valiente Moro |
author_sort |
Morgane Guégan |
title |
The mosquito holobiont: fresh insight into mosquito-microbiota interactions |
title_short |
The mosquito holobiont: fresh insight into mosquito-microbiota interactions |
title_full |
The mosquito holobiont: fresh insight into mosquito-microbiota interactions |
title_fullStr |
The mosquito holobiont: fresh insight into mosquito-microbiota interactions |
title_full_unstemmed |
The mosquito holobiont: fresh insight into mosquito-microbiota interactions |
title_sort |
mosquito holobiont: fresh insight into mosquito-microbiota interactions |
publisher |
BMC |
series |
Microbiome |
issn |
2049-2618 |
publishDate |
2018-03-01 |
description |
Abstract The holobiont concept was first developed for coral ecosystems but has been extended to multiple organisms, including plants and other animals. Studies on insect-associated microbial communities have produced strong evidence that symbiotic bacteria play a major role in host biology. However, the understanding of these symbiotic relationships has mainly been limited to phytophagous insects, while the role of host-associated microbiota in haematophagous insect vectors remains largely unexplored. Mosquitoes are a major global public health concern, with a concomitant increase in people at risk of infection. The global emergence and re-emergence of mosquito-borne diseases has led many researchers to study both the mosquito host and its associated microbiota. Although most of these studies have been descriptive, they have led to a broad description of the bacterial communities hosted by mosquito populations. This review describes key advances and progress in the field of the mosquito microbiota research while also encompassing other microbes and the environmental factors driving their composition and diversity. The discussion includes recent findings on the microbiota functional roles and underlines their interactions with the host biology and pathogen transmission. Insight into the ecology of multipartite interactions, we consider that conferring the term holobiont to the mosquito and its microbiota is useful to get a comprehensive understanding of the vector pathosystem functioning so as to be able to develop innovative and efficient novel vector control strategies. |
topic |
Mosquito Pan-microbiota Multiple interactions Symbiosis Adaptation Pathogen transmission |
url |
http://link.springer.com/article/10.1186/s40168-018-0435-2 |
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