Review: Cooperative group trials — Southwest Oncology Group (SWOG) innovations in advanced prostate cancer
The major goals of the Southwest oncology genitourinary (SWOG-GU) committee in the area of advanced prostate cancer are to improve the survival and quality of life (QOL) of patients with advanced prostate cancer. SWOG trials have examined the role of combined androgen blockade, intermittent androgen...
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Series: | Therapeutic Advances in Medical Oncology |
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doaj-0e391bbcb9e348419668f6f4ee382cbd2020-11-25T03:40:13ZengSAGE PublishingTherapeutic Advances in Medical Oncology1758-83402009-09-01110.1177/1758834009343454Review: Cooperative group trials — Southwest Oncology Group (SWOG) innovations in advanced prostate cancerTanya B. DorffCathy M. TangenE. David CrawfordDaniel P. PetrylakCelestia S. HiganoDerek RaghavanDavid I. QuinnNicholas J. VogelzangIan M. ThompsonThe major goals of the Southwest oncology genitourinary (SWOG-GU) committee in the area of advanced prostate cancer are to improve the survival and quality of life (QOL) of patients with advanced prostate cancer. SWOG trials have examined the role of combined androgen blockade, intermittent androgen deprivation, and the early application of chemotherapy in castration-naïve disease. In addition, they have contributed to advancing the current chemotherapy standard of docetaxel plus prednisone, and ongoing trials seek to improve upon that standard. Finally, surrogate endpoints have been identified and markers of treatment response or resistance with novel technology are under active investigation. This review highlights findings from recent SWOG clinical trials for advanced prostate cancer, emphasizing the clinical impact and future applications of the data.https://doi.org/10.1177/1758834009343454 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tanya B. Dorff Cathy M. Tangen E. David Crawford Daniel P. Petrylak Celestia S. Higano Derek Raghavan David I. Quinn Nicholas J. Vogelzang Ian M. Thompson |
spellingShingle |
Tanya B. Dorff Cathy M. Tangen E. David Crawford Daniel P. Petrylak Celestia S. Higano Derek Raghavan David I. Quinn Nicholas J. Vogelzang Ian M. Thompson Review: Cooperative group trials — Southwest Oncology Group (SWOG) innovations in advanced prostate cancer Therapeutic Advances in Medical Oncology |
author_facet |
Tanya B. Dorff Cathy M. Tangen E. David Crawford Daniel P. Petrylak Celestia S. Higano Derek Raghavan David I. Quinn Nicholas J. Vogelzang Ian M. Thompson |
author_sort |
Tanya B. Dorff |
title |
Review: Cooperative group trials — Southwest Oncology Group (SWOG) innovations in advanced prostate cancer |
title_short |
Review: Cooperative group trials — Southwest Oncology Group (SWOG) innovations in advanced prostate cancer |
title_full |
Review: Cooperative group trials — Southwest Oncology Group (SWOG) innovations in advanced prostate cancer |
title_fullStr |
Review: Cooperative group trials — Southwest Oncology Group (SWOG) innovations in advanced prostate cancer |
title_full_unstemmed |
Review: Cooperative group trials — Southwest Oncology Group (SWOG) innovations in advanced prostate cancer |
title_sort |
review: cooperative group trials — southwest oncology group (swog) innovations in advanced prostate cancer |
publisher |
SAGE Publishing |
series |
Therapeutic Advances in Medical Oncology |
issn |
1758-8340 |
publishDate |
2009-09-01 |
description |
The major goals of the Southwest oncology genitourinary (SWOG-GU) committee in the area of advanced prostate cancer are to improve the survival and quality of life (QOL) of patients with advanced prostate cancer. SWOG trials have examined the role of combined androgen blockade, intermittent androgen deprivation, and the early application of chemotherapy in castration-naïve disease. In addition, they have contributed to advancing the current chemotherapy standard of docetaxel plus prednisone, and ongoing trials seek to improve upon that standard. Finally, surrogate endpoints have been identified and markers of treatment response or resistance with novel technology are under active investigation. This review highlights findings from recent SWOG clinical trials for advanced prostate cancer, emphasizing the clinical impact and future applications of the data. |
url |
https://doi.org/10.1177/1758834009343454 |
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