miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression

miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression

Insulin resistance (IR) is one of the key contributing factors in the development of type 2 diabetes mellitus (T2DM). However, the molecular mechanisms leading to IR are still unclear. The implication of microRNAs (miRNAs) in the pathophysiology of multiple cardiometabolic pathologies, including obe...

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Bibliographic Details
Main Authors: Asier Benito-Vicente, Kepa B. Uribe, Noemi Rotllan, Cristina M. Ramírez, Shifa Jebari-Benslaiman, Leigh Goedeke, Alberto Canfrán-Duque, Unai Galicia-García, Diego Saenz De Urturi, Patricia Aspichueta, Yajaira Suárez, Carlos Fernández-Hernando, Cesar Martín
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
microRNA
type 2 diabetes mellitus
miR-27b
insulin signaling
INRS
Online Access:https://www.mdpi.com/1422-0067/21/22/8675

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