Activation of Human Peripheral Basophils in Response to High IgE Antibody Concentrations without Antigens

Activation of Human Peripheral Basophils in Response to High IgE Antibody Concentrations without Antigens

Basophils and mast cells have high affinity IgE receptors (FcεRI) on their plasma membrane and play important roles in FcεRI-associated allergic diseases, such as pollen allergy, food allergy, chronic spontaneous urticarial (CSU), and atopic dermatitis (AD). To date, several...

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Bibliographic Details
Main Authors: Yuhki Yanase, Yoshimi Matsuo, Tomoko Kawaguchi, Kaori Ishii, Akio Tanaka, Kazumasa Iwamoto, Shunsuke Takahagi, Michihiro Hide
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
basophils
IgE antibody
FcεRI
histamine
CD203c
Online Access:http://www.mdpi.com/1422-0067/20/1/45

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