Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
<p>Abstract</p> <p>Background</p> <p>In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segments in the germline. Partitioning the functional antibody sequences...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-12-01
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| Series: | BMC Bioinformatics |