FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis

FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis

The cytokine like protein FAM3D (Fam3D in mice) is highly expressed in the digestive tract with unknown role in colon pathophysiology. Here, by using gene deficient mice, the authors show that Fam3D is critically involved in colon homeostasis, host defense against colitis-associated carcinogenesis,...

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Bibliographic Details
Main Authors: Weiwei Liang, Xinjian Peng, Qingqing Li, Pingzhang Wang, Ping Lv, Quansheng Song, Shaoping She, Shiyang Huang, Keqiang Chen, Wanghua Gong, Wuxing Yuan, Vishal Thovarai, Teizo Yoshimura, Colm O’huigin, Giorgio Trinchieri, Jiaqiang Huang, Shuye Lin, Xiaohong Yao, Xiuwu Bian, Wei Kong, Jianzhong Xi, Ji Ming Wang, Ying Wang
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19691-z

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