Pyroptosis as Inflammatory Cell Death

Pyroptosis as Inflammatory Cell Death

Pyroptosis, caspase-1-dependent inflammatory cell death, is induced by intracellular pathogens or tissue lesions. Procaspase-1 activation, which is essential for the processing of proinflammatory cytokines pro-IL-1β and pro-IL-18, occurs in macromolecular protein complexes, also referred to as infla...

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Bibliographic Details
Main Authors: AA Vartanyan, VS Kosorukov
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2019-03-01
Series:Kliničeskaâ onkogematologiâ
Subjects:
cell death
pyroptosis
caspases
inflammation
innate immunity
Online Access: http://bloodjournal.ru/wp-content/uploads/2020/03/3.pdf

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