Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation

We report the case of a 50-year-old man who was investigated for an incidental finding of a left lung mass following left shoulder pain over a three month period. He also had a significant raised serum alpha-fetoprotein (AFP) level of 29,000, which raised the suspicion of hepatocellular carcinoma wi...

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Main Authors:	Nurul Yaqeen Mohd Esa, Rosdina Zamrud, Nor Salmah Bakar, Marfu’ah Nik Eezamuddeen, Mohd Farhan Hamdan
Format:	Article
Language:	English
Published:	SAGE Publishing 2018-03-01
Series:	Proceedings of Singapore Healthcare
Online Access:	https://doi.org/10.1177/2010105817716185

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spelling	doaj-0ed6e20b147b4e3985ce1ccab152026a2020-11-25T03:24:07ZengSAGE PublishingProceedings of Singapore Healthcare2010-10582059-23292018-03-012710.1177/2010105817716185Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiationNurul Yaqeen Mohd Esa0Rosdina Zamrud1Nor Salmah Bakar2Marfu’ah Nik Eezamuddeen3Mohd Farhan Hamdan4Respiratory Unit, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, MalaysiaRespiratory Unit, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, MalaysiaPathology Discipline, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, MalaysiaOncology Unit, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, MalaysiaMedical Imaging Unit, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, MalaysiaWe report the case of a 50-year-old man who was investigated for an incidental finding of a left lung mass following left shoulder pain over a three month period. He also had a significant raised serum alpha-fetoprotein (AFP) level of 29,000, which raised the suspicion of hepatocellular carcinoma with lung metastases. However, there was no detectable liver lesion on multiphase contrasted tomography of the liver and no significant hypermetabolic nodes or distant metastasis seen in the liver on positron emission tomography scan. A lung biopsy confirmed adenocarcinoma with hepatocellular differentiation that would explain the raised serum AFP level.https://doi.org/10.1177/2010105817716185
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Nurul Yaqeen Mohd Esa Rosdina Zamrud Nor Salmah Bakar Marfu’ah Nik Eezamuddeen Mohd Farhan Hamdan
spellingShingle	Nurul Yaqeen Mohd Esa Rosdina Zamrud Nor Salmah Bakar Marfu’ah Nik Eezamuddeen Mohd Farhan Hamdan Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation Proceedings of Singapore Healthcare
author_facet	Nurul Yaqeen Mohd Esa Rosdina Zamrud Nor Salmah Bakar Marfu’ah Nik Eezamuddeen Mohd Farhan Hamdan
author_sort	Nurul Yaqeen Mohd Esa
title	Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation
title_short	Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation
title_full	Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation
title_fullStr	Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation
title_full_unstemmed	Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation
title_sort	is it liver or lung cancer? an intriguing case of lung adenocarcinoma with hepatoid differentiation
publisher	SAGE Publishing
series	Proceedings of Singapore Healthcare
issn	2010-1058 2059-2329
publishDate	2018-03-01
description	We report the case of a 50-year-old man who was investigated for an incidental finding of a left lung mass following left shoulder pain over a three month period. He also had a significant raised serum alpha-fetoprotein (AFP) level of 29,000, which raised the suspicion of hepatocellular carcinoma with lung metastases. However, there was no detectable liver lesion on multiphase contrasted tomography of the liver and no significant hypermetabolic nodes or distant metastasis seen in the liver on positron emission tomography scan. A lung biopsy confirmed adenocarcinoma with hepatocellular differentiation that would explain the raised serum AFP level.
url	https://doi.org/10.1177/2010105817716185
work_keys_str_mv	AT nurulyaqeenmohdesa isitliverorlungcanceranintriguingcaseoflungadenocarcinomawithhepatoiddifferentiation AT rosdinazamrud isitliverorlungcanceranintriguingcaseoflungadenocarcinomawithhepatoiddifferentiation AT norsalmahbakar isitliverorlungcanceranintriguingcaseoflungadenocarcinomawithhepatoiddifferentiation AT marfuahnikeezamuddeen isitliverorlungcanceranintriguingcaseoflungadenocarcinomawithhepatoiddifferentiation AT mohdfarhanhamdan isitliverorlungcanceranintriguingcaseoflungadenocarcinomawithhepatoiddifferentiation
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Is it liver or lung cancer? An intriguing case of lung adenocarcinoma with hepatoid differentiation

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