TMEM95 is a sperm membrane protein essential for mammalian fertilization

TMEM95 is a sperm membrane protein essential for mammalian fertilization

The fusion of gamete membranes during fertilization is an essential process for sexual reproduction. Despite its importance, only three proteins are known to be indispensable for sperm-egg membrane fusion: the sperm proteins IZUMO1 and SPACA6, and the egg protein JUNO. Here we demonstrate that anoth...

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Bibliographic Details
Main Authors: Ismael Lamas-Toranzo, Julieta G Hamze, Enrica Bianchi, Beatriz Fernández-Fuertes, Serafín Pérez-Cerezales, Ricardo Laguna-Barraza, Raúl Fernández-González, Pat Lonergan, Alfonso Gutiérrez-Adán, Gavin J Wright, María Jiménez-Movilla, Pablo Bermejo-Álvarez
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
fertilization
reproduction
JUNO
IZUMO
Online Access:https://elifesciences.org/articles/53913

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