Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule.
Proper physiological function in the pre- and post-natal proximal tubule of the kidney depends upon the acquisition of selective permeability, apical-basolateral epithelial polarity and the expression of key transporters, including those involved in metabolite, toxin and drug handling. Particularly...
Main Authors: | Thomas F Gallegos, Gleb Martovetsky, Valentina Kouznetsova, Kevin T Bush, Sanjay K Nigam |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3396597?pdf=render |
Similar Items
-
Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes
by: Wei Wu, et al.
Published: (2017-07-01) -
Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs.
by: Christopher Zhu, et al.
Published: (2015-01-01) -
Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs
by: Darcy C. Engelhart, et al.
Published: (2020-03-01) -
<i>Drosophila</i> SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress
by: Darcy C. Engelhart, et al.
Published: (2020-03-01) -
Downregulation of organic cation transporters OCT1 (<it>SLC22A1</it>) and OCT3 (<it>SLC22A3</it>) in human hepatocellular carcinoma and their prognostic significance
by: Heise Michael, et al.
Published: (2012-03-01)