Involvement of dopamine loss in extrastriatal basal ganglia nuclei in the pathophysiology of Parkinson’s disease

Involvement of dopamine loss in extrastriatal basal ganglia nuclei in the pathophysiology of Parkinson’s disease

Parkinson’s disease is a neurological disorder characterized by the manifestation of motor symptoms, such as akinesia, muscle rigidity and tremor at rest. These symptoms are classically attributed to the degeneration of dopamine neurons in the pars compacta of substantia nigra (SNc), which results i...

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Bibliographic Details
Main Authors: Abdelhamid eBenazzouz, Omar eMamad, Pamphyle eAbedi, Rabia eBouali-Benazzouz, Jonathan eChetrit
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Basal Ganglia
Dopamine
Globus Pallidus
Subthalamic Nucleus
Parkinson’s disease
Extrastriatal dopamine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00087/full

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